Concurrent with T-zone lymphoma and high-grade gastrointestinal cytotoxicT-cell lymphoma in a dog

The Journal of Veterinary Medical Science

Tetsuya SHIMODA¹  Akihisa SUWA¹ 

[1]Sanyo Animal Medical Center, 357-1 Komoto, Akaiwa,Okayama 709-0821, Japan

关键词: canine;    gastrointestinal lymphoma;    large granular lymphocytic lymphoma;    PARR;    T-zone lymphoma;   

DOI  :  10.1292/jvms.16-0542

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

A 9-year-old, spayed female Golden Retriever dog was referred to us for lymphocytosis andlymphadenopathy, secondary to suspected chronic lymphocytic leukemia (CLL). The dog had aclinical history of anorexia, vomiting and melena lasting two days. The popliteal lymphnode contained small-to-intermediate lymphocytes, which led us to suspect low-gradelymphoma. Thickened lesions in the stomach and small intestine were detected byultrasonography. Histopathology of the popliteal lymph node and small intestine revealed asimultaneous presence of T-zone lymphoma (TZL) and high-grade gastrointestinal (GI)cytotoxic T-cell lymphoma. Large granular lymphocytes (LGLs) were seen on cytologicalexamination. Polymerase chain reaction (PCR) revealed that both lymphomas originated inthe T-cells. The dog died 15 days after diagnosis, despite chemotherapy.

【 授权许可】

Unknown