Pathogenic characterization of Erysipelothrix rhusiopathiae Met-203 type SpaA strains from chronic and subacute swine erysipelas in Japan

The Journal of Veterinary Medical Science

Yohko SHIMAZAKI¹  Kinya YAMAMOTO¹  Hidetaka NAGAI¹  Fumiya HIRANO¹  Mariko UCHIYAMA¹  Akemi KOJIMA¹  Yukari ISSHIKI¹  Mayumi KIJIMA¹ 

[1] National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1-15-1 Tokura, Kokubunji, Tokyo 185-8511, Japan

关键词: Erysipelothrix rhusiopathiae;    pathogenicity;    pig;    spaA;   

DOI  :  10.1292/jvms.16-0164

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

To characterize the Erysipelothrix rhusiopathiae Met-203 type surface protective antigen (Spa) A strains causing swine erysipelas in Japan, the nucleotide sequence of the hypervariable region of the spaA gene was determined in 80 E. rhusiopathiae (serotype 1a) isolates collected from pigs with chronic and subacute swine erysipelas in 14 prefectures in 2008–2014. In this study, 14 (17.5%) isolates were Met-203 type SpaA strains. We confirmed the pathogenicity of a Met-203 type SpaA strain in specific-pathogen-free pigs. In this experiment, the two challenged pigs displayed arthritis, urticaria and other clinical signs, but recovered within 10 days. Our results reveal the existence of the E. rhusiopathiae Met-203 type strains that have been causing chronic erysipelas in Japan.

【 授权许可】

Unknown