The Journal of Veterinary Medical Science | |
Pathogenic characterization of Erysipelothrix rhusiopathiae Met-203 type SpaA strains from chronic and subacute swine erysipelas in Japan | |
Yohko SHIMAZAKI1  Kinya YAMAMOTO1  Hidetaka NAGAI1  Fumiya HIRANO1  Mariko UCHIYAMA1  Akemi KOJIMA1  Yukari ISSHIKI1  Mayumi KIJIMA1  | |
[1] National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1-15-1 Tokura, Kokubunji, Tokyo 185-8511, Japan | |
关键词: Erysipelothrix rhusiopathiae; pathogenicity; pig; spaA; | |
DOI : 10.1292/jvms.16-0164 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
To characterize the Erysipelothrix rhusiopathiae Met-203 type surface protective antigen (Spa) A strains causing swine erysipelas in Japan, the nucleotide sequence of the hypervariable region of the spaA gene was determined in 80 E. rhusiopathiae (serotype 1a) isolates collected from pigs with chronic and subacute swine erysipelas in 14 prefectures in 2008â2014. In this study, 14 (17.5%) isolates were Met-203 type SpaA strains. We confirmed the pathogenicity of a Met-203 type SpaA strain in specific-pathogen-free pigs. In this experiment, the two challenged pigs displayed arthritis, urticaria and other clinical signs, but recovered within 10 days. Our results reveal the existence of the E. rhusiopathiae Met-203 type strains that have been causing chronic erysipelas in Japan.
【 授权许可】
Unknown
【 预 览 】
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RO201902196240796ZK.pdf | 743KB | download |