Silicon microgrooves for contact guidance of human aortic endothelial cells

Beilstein Journal of Nanotechnology

关键词: cell morphology;    contact guidance;    microgrooves;    silicon;    human aortic endothelial cells (HAECs);   

DOI  :  10.3762/bjnano.8.72

学科分类：地球科学(综合)

来源: Beilstein - Institut zur Foerderung der Chemischen Wissenschaften

【 摘 要 】

Background: Micro- and nanoscale substrates have been fabricated in order to study the influence of the topography on the cellular response. The aim of this work was to prepare different collagen-coated silicon substrates displaying grooves and ridges to mimic the aligned and elongated endothelium found in linear vessels, and to use them as substrates to study cell growth and behaviour.

【 授权许可】

CC BY