Comparison of cortisol and thyroid hormones between tuberculosis-suspect andhealthy elephants of Nepal

The Journal of Veterinary Medical Science

Ishwari P. DHAKAL¹  Sharada THAPALIYA¹  Kamal P. GAIRHE²  Susan K. MIKOTA³  Toshio TSUBOTA⁴  Sarad PAUDEL⁴  Michito SHIMOZURU⁴  Janine L. BROWN⁵ 

[1] Agriculture and Forestry University, Rampur, Chitwan,Nepal;Department of National Parks and Wildlife Conservation,Kathmandu, Nepal;Elephant Care International, 166 Limo View Lane,Hohenwald, TN 38462, U.S.A.;Laboratory of Wildlife Biology and Medicine, GraduateSchool of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku,Sapporo, Hokkaido 060–0818, Japan;Smithsonian Conservation Biology Institute, Center forSpecies Survival, Front Royal, VA, U.S.A.

关键词: Asian elephant;    cortisol;    thyroxine;    triiodothyronine;    tuberculosis;   

DOI  :  10.1292/jvms.16-0212

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

We compared cortisol and thyroid hormone (T3 and T4) concentrations between tuberculosis(TB)-suspected (n=10) and healthy (n=10) elephants of Nepal. Whole blood was collectedfrom captive elephants throughout Nepal, and TB testing was performed using the ElephantTBSTAT-PAK® and DPP VetTB® serological assays that detect antibodiesagainst Mycobacterium tuberculosis and M. bovis inelephant serum. Cortisol, T3 and T4 were quantified by competitive enzyme immunoassays,and the results showed no significant differences in hormone concentrations betweenTB-suspect and healthy elephants. These preliminary data suggest neither adrenal northyroid function is altered by TB disease status. However, more elephants, including thosepositively diagnosed for TB by trunk wash cultures, need to be evaluated over time toconfirm results.

【 授权许可】

Unknown