Effect of burdock extract on physical performance and physiological fatiguein mice

The Journal of Veterinary Medical Science

Wen-Chyuan CHEN¹  Yi-Ju HSU²  Chi-Chang HUANG³  Hua Shuai LI⁴  Mon-Chien LEE⁴  Fu-An CHEN⁴  Chun-Sheng HO⁴ 

[1] Center for General Education, Chang Gung University ofScience and Technology, Taoyuan 33301, Taiwan;Department of Otorhinolaryngology, Head and NeckSurgery, Sleep Center, Linkou-Chang Gung Memorial Hospital, Taoyuan 33301,Taiwan;Division of Physical Medicine and Rehabilitation,Lo-Hsu Foundation, Inc., Lotung Poh-Ai Hospital, Yilan 26546,Taiwan;Graduate Institute of Sports Science, National TaiwanSport University, Taoyuan 33301, Taiwan

关键词: anti-fatigue;    burdock;    endurance;    grip strength;    toxicity;   

DOI  :  10.1292/jvms.17-0345

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Burdock (BD) is a common vegetable with many pharmacological properties. However, fewstudies have examined the effect of BD on exercise performance and physical fatigue. Weaimed to evaluate the potential beneficial effects of BD on fatigue and ergogenicfunctions following physical challenge in mice. Methods Male ICR mice were divided intofour groups to receive either vehicle, or BD at 348.5, 697 or 1,742.5 mg/kg/day, by dailyoral gavage for 4 weeks. Exercise performance and fatigue were evaluated from forelimbgrip strength, exhaustive swimming time, and post-exercise levels of physicalfatigue-related biomarkers serum lactate, ammonia, glucose, and creatine kinase (CK).Results BD supplementation elevated endurance and grip strength in a dose-dependentmanner. It also significantly decreased lactate, ammonia, and CK levels after physicalchallenge. In addition, BD supplementation had few subchronic toxic effects. ConclusionsSupplementation with BD has a wide spectrum of bioactive effects, including healthpromotion, performance improvement, and fatigue reduction.

【 授权许可】

Unknown