Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata

Acta Crystallographica Section E: Crystallographic Communications

Do, N.Q.N.¹  Bauri, A.K.²  Foro, S.³ 

[1] Accident & Emergency Department, Franco, Vietnamese Hospital, 7-Nguyen, Luong Bang Street, HoChiMinh City, Vietnam;Bioorganic Division, Bhabha Atomic Research Centre, Trombay, Mumbai 85, India;Clemens Schöpf-Institut für Organische, Chemie und Biochemie, Technische Universität Darmstadt, Petersenstrasse 22, D-64287 Darmstadt, Germany

关键词: CRYSTAL STRUCTURE;    SESQUITERPENE;    ISOLATION;    ARTEMISIA RETICULATA;    ANTIPROLIFERATIVE PROPERTY;   

DOI  :  10.1107/S2056989016003236

学科分类：数学（综合）

来源: International Union of Crystallography

【 摘 要 】

The title compound, C15H24O2 {systematic name: 1-[6-hy­droxy-7-(propan-2-yl)-4-methyl­idene-2,3,3a,4,5,6,7,7a-octa­hydro-1H-inden-1-yl]ethanone} was iso­la­ted from A. reticulata by column chromatography over silica gel by gradient solvent elution. The mol­ecule comprises a bi­cyclo­[4.3.0]nonane ring bearing acet­oxy, hy­droxy and isopropyl substituents, and an exocyclic double bond on the cyclo­hexane ring. In the bicyclic skeleton, the cyclo­hexane ring adopts a chair conformation ring and the cyclo­pentane ring is in an envelope conformation. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, forming chains along [010]. These chains are cross-linked by C—H⋯O hydrogen bonds.

【 授权许可】

CC BY