Pharmacognostical, Phytochemical, Pharmacological properties and Toxicological assessment of Phyllanthus amarus

International Journal of Biomedical and Advance Research

Hemant Dhongade ; A. V. Chandewar

关键词: s Phyllanthus amarus;    euphorbiaceae;    phyllanthin;    hypophyllanthin;    pharmacological activities;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Phyllanthus amarus Schum. & Thonn. (Euphorbiaceae) is a small herb well known for its medicinal properties and widely used worldwide. P. amarus is reported to contain variety of phytoconstituents like lignans namely phyllanthin, hypophyllanthin, nirphyllin and phyllnirurin; flavanone glycosides like niranthin, nirtetralin, phyltetralin and lintetralin; a steroidal hormone estradiol; flavanoids like quercetin, quercitrin, and astragalin; triterpenes like phyllanthenol, phyllanthenone and phyllantheol are some of the important constituents. P. amarus is an important plant of Indian Ayurvedic system of medicine which is used in the problems of stomach, genitourinary system, liver, kidney and spleen. It is bitter, astringent, stomachic, diuretic, febrifuge and antiseptic. The whole plant is used in gonorrhea, menorrhagia and other genital affections. It is useful in gastropathy, diarrhoea, dysentery, intermittent fevers, ophthalmopathy, scabies, ulcers and wounds. P. amarus show a wide spectrum of pharmacological activities including antiviral, antibacterial, antiplasmodial, anti-inflammatory, antimalarial, antimicrobial, anticancer, antidiabetic, hypolipidemic, antioxidant, hepatoprotective nephroprotective and diurectic properties. The present work is therefore an effort to give an detailed survey of literature on pharmacognostical, traditional, phytochemical and pharmacological properties of P. amarus.

【 授权许可】

CC BY