HYPOLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF DAUCUS CAROTA SEEDS IN NORMAL RATS

International Journal of Biomedical and Advance Research

Kamlesh Singh ; Hemant Dhongade ; Nisha Singh ; Pranita Kashyap

关键词: s Daucus carota seeds extract;    Lovastatin;    antioxidant;    Hypolipidemic activity;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Objective: Hypolipidemic activity of ethanolic extract of Daucus carota seeds in Normal rats. Method: Rats were divided in to 4 groups. First control group, treated with vehicle only for 7 days. Second group was standard, treated with lovastatin (7.2mg/kg) for 7 days. Third and fourth group were test, treated with Daucus carota seeds extract (200mg/kg and 400mg/kg) for 7 days. 8th day blood sample was collected by retro orbital route and lipid profiles were estimated in serum. Result and Conclusions: Standard and test (400mg/kg DCSE) groups were showed significant (P <0.001) reduction in the total cholesterol, triglyceride HDL and VLDL as compared control group. Test group (200mg/kg) was showed significant (P <0.05) reduction as compared control group. The antioxidant potential of Daucus carota seeds has contributed to the reduction of oxidative stress and Lipid levels in experimental rats.

【 授权许可】

CC BY