Study of microalbuminuria in Diabetes Type 2 patients as a marker of morbidity (A study of 100 cases in Rajkot city)

International Journal of Biomedical and Advance Research

Bhoomika P Dadhania ; Amit H Aravat ; Gauravi A Dhruva

关键词: s Microalbuminuria;    diabetes mellitus;    urine albumin;    diabetic nephropathy;   

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Background: - Diabetes is a stage of persistent hyperglycemia due to absolute or relative deficiency of insulin. About 20-40% of patients with type 2 diabetes develop evidence of nephropathy. Diabetic nephropathy is first recognized as proteinuria. Microalbuminuria is defined as the range in between urinary excretion of albumin of 20-200 µg/min or 30-300 mg/24 hrs with a negative dipstick test. Methods: - The study was carried out on 100 patients of diabetes type 2 having more than five years duration of diabetes in Pathology Department. Patient’s age, age at detection, sex, duration of diabetes, levels of Fasting Blood Sugar(FBS), Postprandial Blood Sugar (PP2BS), Urea, Creatinine, Cholesterol, Glycosylated Hemoglobin(HbA1C). Results: - We found prevalence of microalbuminuria in present study to be 50%. A high percentage of hypertensive patients, patients having high FBS, PP2BS, cholesterol developed microalbuminuria. The group of patients having high urea and high creatinine has higher prevalence of microalbuminuria.  Higher prevalence of microalbuminuria was seen in patients having high HbA1C.  Conclusion: -As it is possible to halt or delay the progression of diabetic nephropathy by the use of appropriate treatment modalities such as angiotensin converting enzyme inhibitors at this stage, the study is helpful thereby in reducing morbidity and increasing life expectancy of patients with diabetes mellitus type 2.

【 授权许可】

CC BY