Rapid and simple analysis of trace levels of three explosives in soil by liquid chromatography—tandem mass spectrometry

Acta Chromatographicae

Gül Fidan Yenel Avci¹  Beril Anilanmert¹  Salih Cengiz² 

[1] Istanbul University Institute of Forensic Sciences, 34303, Cerrahpasa/Istanbul, Turkey;Istanbul University Institute of Forensic Sciences, 34303, Cerrahpasa/Istanbul, Turkey E-mail: [e-mail]

关键词: explosive analysis in soil;    TNT;    RDX;    HMX;    determination with LC—ESI—MS/MS;    validation;   

DOI  :  10.1556/1326.2017.29.1.03

学科分类：化学（综合）

来源: Akademiai Kiado Rt.

【 摘 要 】

The analysis of trace levels of explosives in post-blast debris is critical in homeland security, environmental analysis, and crime scene forensic investigations. A fast and a selective determination method with high recovery was developed for the common explosives 2,4,6-trinitrotoluene (TNT), 3,5-trinitro-1,3,5-triazacyclohexane (RDX), and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in soil, using liquid chromatography—tandem mass spectrometry (LC—MS/MS). An easy and practical sample preparation method was developed using 4.00 mL acidified acetone with 0.25% HCl. After the easy evaporation of acetone extract, 10 min LC—MS/MS analysis provided a clear separation in column. Short duration of the whole procedure allows the use of this method in routine analysis. As a result of the analysis performed in spiked soils in 50.0, 100.0, and 250.0 ng g−1 concentrations, high recoveries such as 100.4 (±8.8)% for RDX, 96.9 (±10.5)% for HMX, and 97.6 (±13.9)% for TNT were obtained. Limit of detection (LOD) and limit of quantification (LOQ) values obtained from the analysis of the spiked soils were 4.3 ng g−1 and 7.00 ng g−1 for RDX, 6.8 ng g−1 and 10.0 ng g−1 for HMX, and 18.9 ng g−1 and 38.0 ng g−1 for TNT, respectively. The Horwitz Ratio (HorRat) calculation was used to evaluate if the inter-day and inter-analyst precisions were in the acceptable limits. The method was successfully applied to three artificial explosion samples for detection of explosives.

【 授权许可】

Unknown