Biological activities of lignans from Taxus baccata L. growing in Turkey

Dynamic Chiropractic

关键词: Taxus baccata;    taxaceae;    lignans;    anti-inflammatory;    antinociceptive;    anti-ulcerogenic;    antimicrobial;    cytotoxicity;    enzyme inhibitory;    antioxidant.;   

DOI  :  10.5897/JMPR09.431

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Phytochemical investigation ofTaxus baccataL. (Taxaceae) by successive chromatographic methods resulted in the isolation of the lignans; lariciresinol (1), taxiresinol (2), 3'-demethylisolariciresinol-9'-hydroxyisopropylether (3), isolariciresinol (4) and 3-demethylisolariciresinol (5) as well as taxoids. Compounds 1 - 5 were evaluated for their several biological activities such as anti-inflammatory, antinociceptive, anti-ulcerogenic, antimicrobial, cytotoxic, and antioxidant as well as acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and lipoxygenase (LOX) inhibitory activities. In this review, the diverse biological activity profiles of lignan derivative compounds (1 - 5) obtained fromT. baccatagrowing in Turkey will be discussed.

【 授权许可】

Unknown