Comparison of biological activities of Ribes fasciculatum according to regional differences

Dynamic Chiropractic

Ju-Sung Kim¹  Yeo-Jin Sa²  Tae Kyung Hyun³ 

[1] College of Applied Life Sciences, Jeju National University, Jeju 690-756, Korea.;Department of Applied Plant Sciences, Kangwon National University, Chuncheon 200-701, Korea.;Division of Applied Life Science (BK21 program), Gyeongsang National University, Jinju 660-701, Korea.

关键词: Anti-oxidant activity;    anti-microbial activity;    alpha glucosidase inhibitory effect;    Ribes fasciculatum.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Ribes fasciculatumhas been traditionally used as febrifuge, diuretic and antidote against urushiolin Korea, although its biological functions have not been well studied. In this study, we determined the anti-oxidant activities, anti-microbial activities and α-glucosidase inhibitory effects of methanol extract and the fractions ofR. fasciculatumstem from Chuncheon and Jeju in South Korea. The highest anti-oxidant activity obtained by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay and reducing power assay was found in the EtOAc fraction from Jeju-MeOH extract, which contained the highest level of total phenolic compounds compared to the other fractions. In addition, EtOAc fraction from Chuncheon-MeOH extract exhibited higher inhibitory activities against α-glucosidase (IC50= 4.38 ug/ml) compared to the IC50of the EtOAc fraction from Jeju-MeOH extract. Chuncheon-MeOH extract showed antimicrobial activities againstStaphylococus aureus,Escherichia coliandPichia jadinii. Although, extracts obtained from two regions contained different biological activities, thesein vitrostudies indicate that this plant can likely be a potential medicinal plant resource for developing effective dietary health supplements.

【 授权许可】

Unknown