Pharmacological activities of selected plant species and their phytochemical analysis

Dynamic Chiropractic

Maryam Jamil¹  Bushra Mirza² 

[1] Department of Biochemistry, Quaid I Azam University, (45320) Islamabad, Pakistan.;Department of Plant Sciences, Quaid I Azam University, (45320) Islamabad, Pakistan.

关键词: Antitumor;    cytotoxicity;    plant extracts;    plant growth regulatory factors;    phytochemical constituents.;   

DOI  :  10.5897/JMPR09.259

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

In this study, four plants [Chrozophora hierosolymitanaSpreng (Euphorbiaceae), Ephedra gerardianaWall. ex Stapf (Ephedraceae), Chrysanthemum leucanthemumL. (Astraceae),andQuercus dilatataL. (Fegaceae)] collected from different regions of Pakistan were screened to identify any chemotherapeutic agents present in them. Seven methanol extracts of these plants (leaf, stem, and root extracts ofC. hierosolymitana; stem and root extracts ofE. gerardiana; aerial parts ofC. leucanthemum,andaerial parts ofQ. dilatata) were examined for cytotoxicity using brine shrimp assay, antitumor activity using potato disc assay, and phytotoxicity activity using radish seed bioassay. Two methanol plant extracts, that is, leaf extract ofC. hierosolymitanaand root extract ofE. gerardianashowed significant brine shrimp cytotoxicity activity ranging from 171.55 to 523.8 ppm. Six of the seven extracts exhibited tumor inhibition at all the three concentrations tested, ranging from 10 to 80%. All extracts showed growth and seed germination inhibition at high concentration against radish seeds, while two extracts (root extract ofC. hierosolymitanaand aerial parts ofQ. dilatata)showed growth stimulating effects at lower concentrations.Phytochemical tests showed the presence of alkaloids, saponins, anthraquinones, terpenoids, flavonoids, flavones, tannins, phlobatannins, and cardiac glycosides in different concentrations in these extracts.

【 授权许可】

Unknown