Antibacterial and phytochemical screening of methanolic extract of Celosia leptostachya Benth leaves on some selected clinical isolates

Dynamic Chiropractic

Umar K. J.²  ala M.³  Garba M.⁴  Narsquo⁴  Rabah A. B.⁵  Ibrahim M. L.⁶  Bello M.^1,10 

[1]  Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Department Nigeria.;Sokoto State, State, State,Nigeria.;of Chemistry, Federal College of Education (Technical), Gusau, Zamfara, Zamfara of Chemistry, Shehu Shagari College of Education, Sokoto, Sokoto of Microbiology, Usmanu Danfodiyo University, Sokoto, Sokoto 

关键词: Phytochemical;    antibacterial;    methanolic extract;    CelosialeptostachyaBenth.;   

DOI  :  10.5897/JMPR10.231

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The antibacterial screening ofCelosialeptostachyaBenthleaveswas carried out using the agar well diffusion technique andthe methanolic extract oftheleaves showed considerable activity onEscherichiacoliandStaphyllococcus aureusboth at 60 and 80 mg/mlwith zones of inhibition of 15.50, 18.00 and 16.50, 19.00 mm respectively. Whereas, itshowed activity only ataconcentration of 80 mg/mlwith azone of inhibitionof 17.50 mm onSalmonella typhi. However, theC.leptostachyaBenth extract showed no activity onShigella dysentriae.Thephytochemicalproperties of the extract were also determined.Theresultreveals the presence of alkaloids, flavonoids, cardiac glycosides, and tannins,whereasphlobatannins, anthraquinones, steroids and saponins werenot detected in the extract. The extractcontainssome major bioactive compound that inhibit the growth of microorganismsthereby proving very effective as alternative source of antibiotics.

【 授权许可】

Unknown