Total phenols, antioxidant potential and antimicrobial activity of the methanolic extracts of Ephedra laristanica

Dynamic Chiropractic

Abdolhossein Rustaiyan¹  Mohammad Kazem Mohammadi²  Mohammad Hossein Farjam³  Katayoun Javidnia⁴ 

[1] Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran.;Department of Food Science and Technology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran.;Faculty of Science, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.;Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medicinal Sciences, Shiraz, Iran.

关键词: Antioxidant(s);    ferric reducing antioxidant power (FRAP);    2;    2-diphenyl-1-picrylhydrazyl (DPPH);    total phenol;    antimicrobial.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

The antioxidant activities of the methanolic extracts ofEphedra laristanicagrowing in Iran were evaluated using ferric reducing antioxidant power (FRAP) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays. FRAP values 2.1 mmol eq quercetin/g extracts, and IC50values in the DPPH assay 4.6 mg/mL. This plant showed the high antioxidant activities. FRAP and DPPH assay results showed good correlations with the total phenolic contents of the plants, measured by the Folin-Ciocalteau assay (r2= 0.926 and 0.913, respectively, p < 0.0001). The antimicrobial capacity was screened against Gram positive and Gram negative bacteria, and fungi. The extract inhibited the growth of Gram negative bacteria, beingEscherichia colithe most susceptible one with MIC of 32 μg/mL for the extract. The results obtained indicate thatE. laristanicamay become important in the obtainment of a noticeable source of compounds with health protective potential and antimicrobial activity.

【 授权许可】

Unknown