RP-HPLC analysis for camptothecin content in Nothapodytes nimmoniana, an endangered medicinal plant

Dynamic Chiropractic

关键词: Nothapodytes nimmoniana;    Icacinaceae;    HPLC;    secondary metabolite;    alkaloid;    quinoline;    camptothecin.;   

DOI  :  

学科分类：医学（综合）

来源: MPA Media

【 摘 要 】

Studies were carried out on analysis of secondary metabolites by RP-HPLC from different parts (bothin- vitroand-vivo) ofNothpodytes nimmoniana, an endangered medicinal plant. HPLC analysis showed the presence of camptothecin, a medicinally important alkaloid fromN. nimmoniana. Theplant parts used for the analysis include leaves, seeds, seed coat and leaf derived callus. Among all the plant parts used, seeds recorded maximum (0.040%) camptothecin content followed by dried leaf samples. Seed coat recorded least camptothecin content. The study indicated that almost all parts of the plant contain camptothecin.

【 授权许可】

Unknown