Bloodstream Infection Due to CTX-M-15 and TEM-1 Extended-Spectrum β-Lactamase-Producing Salmonella enterica serovar Virchow ST16

Japanese journal of infectious diseases

Joo-Hee Hwang¹  Chang-Seop Lee²  Jeong-Hwan Hwang³  Gee-Wook Shin⁴ 

[1] Biomedical Research Institute of Chonbuk National University Hospital;Biosafety Reference Center and College of Veterinary Medicine, Chonbuk National University;Department of Internal Medicine, Chonbuk National University;Research Institute of Clinical Medicine, Chonbuk National University

关键词: Salmonella enterica serovar Virchow;    CTX-M-15;    TEM-1;   

DOI  :  10.7883/yoken.JJID.2016.142

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

A 57-year-old man presented with high fever and diarrhea. A blood culture revealed the presence of a Group C nontyphoidal Salmonella (NTS) isolate. On Salmonella serotyping, the isolate was identified as Salmonella enterica serovar Virchow. Its sequence type was determined to be ST16 by sequence analysis of 7 different housekeeping genes. The blaCTX-M group 1 and blaTEM genes were amplified using multiplex PCR assay for detecting extended-spectrum β-lactamases (ESBL) genes. Sequences of both amplicons were respectively identical to CTX-M-15- and TEM-1-encoding genes. Since NTS is a cause of foodborne illness outbreaks in communities and an important cause of community-acquired bloodstream infection, clinicians should consider ESBL- or AmpC-producing NTS species in the differential diagnosis.

【 授权许可】

Unknown