An Ecological Survey of Mosquitoes and the Distribution of Japanese Encephalitis Virus in Ishikawa Prefecture, Japan, between 2010 and 2014

Japanese journal of infectious diseases

Tsutomu Takegami¹  Yoko Kitagawa¹  Kiyoe Hori¹  Yosaburo Oikawa²  Manabu Murakami²  Kiyoshi Kamimura³ 

[1] Department of Life Science, Medical Research Institute, Kanazawa Medical University;Department of Medical Zoology Kanazawa Medical University;Marusan Pharma Biotech

关键词: Japanese encephalitis virus;    flavivirus;    CDC light trap;    Culex tritaeniorhynchus;   

DOI  :  10.7883/yoken.JJID.2016.263

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

Japanese encephalitis virus (JEV) is a flavivirus, responsible for over 30,000 annual cases of encephalitis worldwide, with a mortality rate of approximately 30%. Therefore, it is important to examine the distribution of mosquitos carrying JEV in the fields, even though recently, the number of Japanese encephalitis cases has been approximately 5 per year in Japan. We report the seasonal dynamics of mosquitoes between 2010 and 2014 in Ishikawa Prefecture, Japan. We collected 39,308 female adult mosquitoes, 98.2% of which were classified as Culex tritaeniorhynchus Giles. We identified JEV genomic RNA belonging to genotype 1 from the homogenate of Cx. tritaeniorhynchus, collected during our study using reverse transcription-PCR and nucleotide sequencing techniques. Our results indicate that mosquito vectors for JEV are distributed not only in areas in Ishikawa, but also throughout Japan, and the results suggest that we must be careful regarding JEV outbreaks in Japan in the future.

【 授权许可】

Unknown