How “Humane” Is Your Endpoint?—Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection

PLoS Pathogens

Nuno H. Franco¹  I. Anna S. Olsson²  Margarida Correia-Neves³ 

[1] IBMC - Institute for Molecular and Cell Biology (Laboratory Animal Science Group), University of Porto, Porto, Portugal;ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal;Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal

关键词: Tuberculosis;    Animal welfare;    Biomarkers;    Mouse models;    Animal models of infection;    Mycobacterium tuberculosis;    Veterinary diseases;    Research validity;   

DOI  :  10.1371/journal.ppat.1002399

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

CC BY