Plasmonic Nanocavities-based Aperiodic crystal for Protein-Protein Recognition SERS sensors

Optical Data Processing and Storage

M. Rippa¹ 

关键词: Photonic Crystals;    Plasmonics;    Sensors;    Nanofabrication;    Nanolithography;    Raman;    Surface Enhanced Raman Scattering (SERS);    Localized Surface Plasmonic Resonance (LSPR);    Metamaterials;   

DOI  :  10.1515/odps-2017-0007

学科分类：电子、光学、磁材料

来源: De Gruyter

【 摘 要 】

AbstractThe revelation of protein-protein interactions is one of the main preoccupations in the field of proteomics. Nanoplasmonics has emerged as an attractive surface-based technique because of its ability to sense protein binding under physiological conditions in a label-free manner. Here, we present a detailed experimental study of the use of aperiodic photonic nanocavities for plasmonic Surface Enhanced Raman Scattering (SERS) protein detection and recognition. The plasmonic crystal is designed on a 2D Thue-Morse array configuration. The SERS nanosensor is coated with a proper self-assembled monolayer to covalently bind Bovine Serum Albumin that is a well known model to study biological (specifically, protein) systems. The performance of the nanosensor is assessed by recording a new Raman (SERS) peak in the fingerprint region and by a giant enhancement of the SERS signal intensity, both reported and discussed.

【 授权许可】

CC BY-NC-ND