De Novo Synthesis of VP16 Coordinates the Exit from HSV Latency In Vivo

PLoS Pathogens

Richard L. Thompson¹  Nancy M. Sawtell²  Chris M. Preston³ 

[1] Department of Molecular Genetics, Microbiology, and Biochemistry,University of Cincinnati School of Medicine, Cincinnati, Ohio, United States ofAmerica;Department of Pediatrics, Division of Infectious Diseases, CincinnatiChildren's Hospital Medical Center, Cincinnati, Ohio, United States ofAmerica;Medical Research Council Virology Unit, Glasgow, Scotland, UnitedKingdom

关键词: Neurons;    Viral replication;    Ganglia;    Viral persistence;    latency;    Viral genome;    Lytic cycle;    Gene expression;    Herpes simplex virus;   

DOI  :  10.1371/journal.ppat.1000352

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

CC BY