COMPARATIVE STUDIES OF LEWIS ACIDITY OF ALKYL-TIN CHLORIDES IN MULTICOMPONENT BIGINELLI CONDENSATION USING GRINDSTONE CHEMISTRY TECHNIQUE

Journal of The Chilean Chemical Society

SINGH, HAR LAL¹  SAROJ, REKHA¹  SACHDEVA, HARSHITA¹  KHATURIA, SARITA¹ 

[1] Mody Institute of Technology and Science, Lakshmangarh, India

关键词: Lewis Acids;    Dihydropyrimidinones;    Biginelli condensation;    Grindstone technique;    SnCl4.5H2O.;   

DOI  :  10.4067/S0717-97072012000100013

学科分类：化学（综合）

来源: Sociedad Chilena de Quimica

【 摘 要 】

A simple and efficient procedure for the one pot Biginelli Condensation Reaction of aldehydes, â-ketoester and urea employing SnCl4.5H2O /mono/di/tri-butyl- tin chloride as a novel catalyst is described. Compared to classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity. Further, comparative efficiency of alkyl- tin chlorides in multicomponent Biginelli Condensation Reaction is also studied under solvent free conditions.

【 授权许可】

Unknown