Systemic Therapy of Advanced/Metastatic Breast Cancer - Current Evidence and Future Concepts

Breast care

Cornelia Liedtke¹ 

关键词: Metastatic breast cancer;    Molecular breast cancer subgroups;    Chemotherapy;    Targeted therapy;    Endocrine therapy;    Clinical trials;   

DOI  :  10.1159/000447549

学科分类：泌尿医学

来源: S Karger AG

【 摘 要 】

Systemic therapy of metastatic breast cancer may include chemotherapy, endocrine therapy, and targeted therapies (e.g., antibody-based approaches). These agents may be employed alone or in combination based on the patient's breast cancer subtype. Therefore, characterization of the disease phenotype is necessary and may include biopsy of the metastatic site. Novel therapeutic approaches include immunologic therapies, PARP inhibitors, PI3K inhibitors, and CDK4/6 inhibitors, which are currently under investigation in clinical trials.

【 授权许可】

CC BY