Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein

PLoS Pathogens

David C. Goldstone¹  Ian A. Taylor¹  Sadayuki Ohkura²  Jonathan P. Stoye²  Kate Holden-Dye²  Melvyn W. Yap² 

[1] Division of Molecular Structure, MRC National Institute for MedicalResearch, London, United Kingdom;Division of Virology, MRC National Institute for Medical Research,London, United Kingdom

关键词: Viral packaging;    Macaque;    HIV-1;    Viral replication;    Rhesus monkeys;    Viral core;    Microbial mutation;    Substitution mutation;   

DOI  :  10.1371/journal.ppat.1002011

学科分类：生物科学（综合）

来源: Public Library of Science

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