Phenolic derivatives and other chemical compounds from Cochlospermum regium

Quimica nova

Macedo, Cristiana dos Santos de¹  Brandão, Luiz Fabrício Gardini²  Carollo, Carlos Alexandre²  Solon, Soraya²  Klein, André³  Dias-Junior, Carlos Alan⁴  Siqueira, João Máximo de⁴ 

[1] Universidade Anhanguera;Universidade Federal de Mato Grosso do Sul, Campo Grande, Brasil;Universidade Federal de Minas Gerais, Belo Horizonte, Brasil;Universidade Federal de São João Del Rei, Divinópolis, Brasil

关键词: Cochlospermum;    antimicrobial activity;    dihydrokaempferol-;    3-;    O-;    β;    -;    (6"-;    galloyl)-;    glucopyranoside.;   

DOI  :  10.1590/S0100-40422012000600019

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature.

【 授权许可】

CC BY