Quimica nova | |
Phenolic derivatives and other chemical compounds from Cochlospermum regium | |
Macedo, Cristiana dos Santos de1  Brandão, Luiz Fabrício Gardini2  Carollo, Carlos Alexandre2  Solon, Soraya2  Klein, André3  Dias-Junior, Carlos Alan4  Siqueira, João Máximo de4  | |
[1] Universidade Anhanguera;Universidade Federal de Mato Grosso do Sul, Campo Grande, Brasil;Universidade Federal de Minas Gerais, Belo Horizonte, Brasil;Universidade Federal de São João Del Rei, Divinópolis, Brasil | |
关键词: Cochlospermum; antimicrobial activity; dihydrokaempferol-; 3-; O-; β; -; (6"-; galloyl)-; glucopyranoside.; | |
DOI : 10.1590/S0100-40422012000600019 | |
学科分类:化学(综合) | |
来源: Sociedade Brasileira de Quimica | |
【 摘 要 】
This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature.
【 授权许可】
CC BY
【 预 览 】
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RO201902010543704ZK.pdf | 242KB | download |