Phenolic derivatives and other chemical compounds from Cochlospermum regium

Química Nova

Soraya Solon²  Carlos Alexandre Carollo²  Luiz Fabrício Gardini Brandão²  Cristiana Dos Santos De Macedo¹  André Klein¹  Carlos Alan Dias-junior¹  João Máximo De Siqueira¹ 

[1] ,Universidade Federal de Mato Grosso do Sul Centro de Ciências Biológicas e da Saúde Campo Grande MS ,Brasil

关键词: Cochlospermum;    antimicrobial activity;    dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside;   

DOI  :  10.1590/S0100-40422012000600019

来源: SciELO

【 摘 要 】

This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License