Natural Killer and Natural Killer T Cells as a Prognostic Factor for Rheumatoid Arthritis and Ankylosing Spondylitis

International Journal of Biomedical Research

Mehmet Soy¹  Akal?n² 

[1] Trakya Universty Medical School, Rheumatology Unit.;[e-mail]

关键词: Ankylosing spondylitis;    diseases activity;    functional capacity;    natural killercells;    natural killerT cells;    rheumatoid arthritis.;   

DOI  :  10.7439/ijbr.v6i5.2004

学科分类：基础医学

来源: Scholar Science Journals

【 摘 要 】

Object: We aimed to show the relationship between natural killer T cells and natural killer cells with diseases activity and functional capacity the patient with rheumatoid arthritis and anklyosing spondylitis.Materials and Methods: Including this study in all the patient was evaluated to the disease activity and functional capacity and radiographic view and also; their hemogram and C- reactive protein, erythrocyte sedimentation rate and rheumatoid factor and natural killer T cells and natural killer cells were measured, simultaneously.Results: It was shown to be the positive correlation between the disease activity with total Sharp score and functional capacity. Significant positive correlation was found to be the between BASDAI score with natural killer T cells. The ratio of natural killer T cells and natural killer cells were found higher, using of the metotreaxate treatments with rheumatoid arthritis patients. No correlation was found the between percentage of natural killer T cells and natural killer cells with using of the metotreaxate treatment in the patients with ankylosing spondylitis .Conclusion: Determination of the levels of natural killer T cells and natural killer cells can cause to estimation of disease course and treatment response and the development of functional disorders in the patients with rheumatoid arthritis and ankylosing spondylitis.

【 授权许可】

CC BY