Cost-effectiveness analysis of rotavirus vaccination among Libyan children using a simple economic model

Libyan journal of medicine

Salem Alkoshi¹ 

关键词: diarrhea;    rotavirus;    cost-effectiveness;    vaccination;    Libya;   

DOI  :  10.3402/ljm.v9.26236

学科分类：医学（综合）

来源: Co-Action Publishing

【 摘 要 】

BackgroundRotavirus infection is a major cause of childhood diarrhea in Libya. The objective of this study is to evaluate the cost-effectiveness of rotavirus vaccination in that country.MethodsWe used a published decision tree model that has been adapted to the Libyan situation to analyze a birth cohort of 160,000 children. The evaluation of diarrhea events in three public hospitals helped to estimate the rotavirus burden. The economic analysis was done from two perspectives health care provider and societal. Univariate sensitivity analyses were conducted to assess uncertainty in some values of the variables selected.ResultsThe three hospitals received 545 diarrhea patients aged≤5 with 311 (57%) rotavirus positive test results during a 9-month period. The societal cost for treatment of a case of rotavirus diarrhea was estimated at US$ 661/event. The incremental cost-effectiveness ratio with a vaccine price of US$ 27 per course was US$ 8,972 per quality-adjusted life year gained from the health care persp...

【 授权许可】

CC BY