Cardiorenal Syndrome Type 1 May Be Immunologically Mediated: A Pilot Evaluation of Monocyte Apoptosis

Cardiorenal medicine

Grazia Maria Virzì ; Rossella Torregrossa ; Dinna N. Cruz ; Chang Y. Chionh ; Massimo de Cal ; Sachin S. Soni ; Massimo Dominici ; Giorgio Vescovo ; Mitchell H. Rosner ; Claudio Ronco

关键词: Acute kidney injury;    Cardiorenal syndrome;    Acute heart failure;    Apoptosis;   

DOI  :  10.1159/000335499

学科分类：心脏病和心血管学

来源: S Karger AG

【 摘 要 】

Abstract Background: Cardiorenal syndrome (CRS) type 1 is characterized by a rapid worsening of cardiac function leading to acute kidney injury (AKI). An immune-mediated damage and alteration of immune response have been postulated as potential mechanisms involved in CRS type 1. In this pilot study, we examined the possible role of the immune-mediated mechanisms in the pathogenesis of this syndrome. The main objective was to analyze in vitro that plasma of CRS type 1 patients was able to trigger.

【 授权许可】

CC BY