Markers of arterial stiffness in a sample of Lebanese subjects with Grade I essential hypertension:

SAGE Open Medicine

SamirMallat¹ 

关键词: Arterial stiffness;    hypertension;    pulse wave velocity;    aging;    Lebanon;   

DOI  :  10.1177/2050312117712886

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objectives:Arterial stiffness is becoming a major global condition associated with an increased risk of cardiovascular problems and death. Several markers have been linked to arterial stiffness.Methods:To determine and evaluate these relations, anthropometric parameters (weight, height, and pulse rate), biochemical profile, and central and peripheral indices of arterial function were measured in 114 Lebanese subjects with Grade I essential hypertension.Results:Age was associated with a higher pulse wave velocity (p = .001), central systolic blood pressure (p = .013), central pulse pressure (p = .028), central augmentation index (p ≤ .0001) with a lower heart rate (p = .08), and glomerular filtration rate (p = .019). Pulse wave velocity was found to be higher in older subjects (>65 years) and correlated with higher body mass index (r = .85) independent of age. Aging also correlated with higher plasma glucose and alterations in calcium–phosphorus metabolism.Conclusion:Aging is associated with increased arte...

【 授权许可】

CC BY