Screening for elevated risk of liver disease in preschool children (aged 2–5 years) being seen for obesity management:

SAGE Open Medicine

Daniel RBeacher¹ 

关键词: Obesity;    children;    liver;    alanine aminotransferase;    nonalcoholic fatty liver disease;   

DOI  :  10.1177/2050312114555211

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objectives:Elevated alanine aminotransferase can heighten concern for the presence of nonalcoholic fatty liver disease in obese children. Guidelines recommend alanine aminotransferase screening of obese children start at the age of 10 years. We examined alanine aminotransferase values routinely obtained for tertiary obesity care among preschool (2–5 years) and school-age children.Methods:Medical records of children attending a tertiary obesity clinic and with alanine aminotransferase measured within 6 months of the initial visit were reviewed. Children with known genetic abnormalities were excluded. Children were grouped by age to focus attention on groups not covered by screening guidelines. Associations with elevated alanine aminotransferase (>30 IU/L) were examined.Results:A total of 284 records were analyzed (73 preschool, 143 young school-age (6–9 years), 68 older school-age (10–11 years)). Children were primarily Hispanic and had body mass index ≥ 99th percentile (preschool children 92%, young schoo...

【 授权许可】

CC BY