Challenges and Considerations in Optimizing Ovarian Stimulation Protocols in Oncofertility Patients

Frontiers in Public Health

Kathryn Coyne¹ 

关键词: oncofertility;    controlled ovarian stimulation;    assisted reproduction;    follicular phase;    luteal phase;   

DOI  :  10.3389/fpubh.2014.00246

学科分类：卫生学

来源: Frontiers

【 摘 要 】

The scope of cancer treatment in women of childbearing age has changed in the last decade. Fertility preservation is no longer an afterthought but central to multi-disciplinary cancer treatment planning and should be addressed due to the cytotoxic effects of cancer therapy. However, oncology patients present as a unique treatment challenge as the physician must balance the urgency of fertility preservation with the risks of delaying cancer therapy. Controlled ovarian stimulation (COS) is routinely applied in assisted reproductive technology but can be contraindicated in women with estrogen-receptor-positive tumors. This paper reviews some of the challenges to consider when using COS and newer stimulation protocols to minimize risks and optimize outcomes in oncofertility patients.

【 授权许可】

CC BY