Lymphadenopathy: Differentiation between Tuberculosis and Other Non-Tuberculosis Causes like Follicular Lymphoma

Frontiers in Public Health

Karan Thakkar¹ 

关键词: CD20;    acid fast bacilli;    Koch’;    s disease;    extrapulmonary tuberculosis;    splenomegaly;    lymphoma;    lymphadenitis;    GeneXpert;   

DOI  :  10.3389/fpubh.2016.00031

学科分类：卫生学

来源: Frontiers

【 摘 要 】

Lymphadenopathy (LD) is a common clinical presentation in outpatient departments (1–3). It is a cause of concern for the patient and physician alike even in the absence of symptoms (4). In India and some other developing countries, tuberculosis (TB) is the first differential diagnosis for a patient who presents with chronic lymph node enlargement (4–6). Nonetheless, studies have shown that more than 50% of cases of LD are due to non-TB causes and, in these cases, excision biopsy (EB) with histopathology and/or microbiological examination, is the only way to exclude TB (2, 5, 7). Malignancies may account for about 1% of cases of LD (1). The causes of LD can be broadly classified as shown below (8–10):.

【 授权许可】

CC BY