Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants

Frontiers in Pediatrics

Eirin Esaiassen¹ 

关键词: gut microbiota;    preterm infant;    shotgun metagenome sequencing;    taxonomy;    bifidobacteria;    lactobacilli;    colonization resistance;   

DOI  :  10.3389/fped.2018.00347

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic therapy on the developing gut microbiota and antibiotic resistome in extremely preterm infants, and to compare with very preterm infants and term infants not given probiotics.

【 授权许可】

CC BY