Abdominal and Thigh Muscle Attenuation Is Associated With Visceral Fat and Age in Children and Adolescents With Obesity:

Global Pediatric Health

HiroshiAkima¹ 

关键词: intramuscular fat;    visceral fat;    obesity;   

DOI  :  10.1177/2333794X18817121

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objective. This study investigated relationships between adipose tissue deposition within skeletal muscle and morphological and biochemical variables in children with obesity. Methods. Fifty-one Japanese children (16 girls) aged 7 to 16 years were assigned to either mild (<20%), moderate (≥20% to <50%), or severe obesity groups (≥50%). Computed tomography images were taken to calculate the cross-sectional area (CSA) of muscle, subcutaneous and visceral adipose tissue (VAT, for abdomen only), and muscle signal intensities, as an index of intramuscular adipose tissue in the anterior, lateral, and posterior muscles of the abdomen and quadriceps, hamstring and adductor muscles in the thigh. Fasting blood samples were collected to measure plasma lipids, glutamate oxaloacetate transaminase, glutamate oxaloacetate transaminase, uric acid, glucose, and HbA1c. Results. Signal intensity in the severe obesity group was significantly lower than mild and moderate obesity groups in the abdomen and significantly lower t...

【 授权许可】

CC BY