Proteomic studies of Anaplasia in Wilms Tumor:

Proteomics Insights

RongFan¹ 

关键词: Wilms tumor;    nephroblastoma;    anaplasia;    tumor markers;    mass spectrometry;    iTRAQ;    proteomics;    ENO1;    GAPDH;    ALDOA;    SLC25A6;    LDHA;    PGAM1;    MIF;    RBP1;    HBA;    HP;    COL1A1;    CFL1;    FSCN1;   

DOI  :  10.4137/PRI.S7466

学科分类：生物科学（综合）

来源: Sage Journals

【 摘 要 】

Wilms tumor is the most common malignant tumor in the pediatric kidney. Anaplasia, focal or diffuse as defined by histological criteria, is the most important parameter to guide the clinical treatment plan. We sought to identify and characterize potential useful biomarkers associated with anaplasia and provide insight into the peculiar molecular biology of Wilms tumor with unfavorable histology.

【 授权许可】

CC BY