Regioselective Friedel-Crafts alkylation of indoles with epoxides using nano MgO

Green Chemistry Letters and Reviews

Mona Hosseini-Sarvari¹ 

关键词: nano MgO;    Friedel-Crafts alkylation;    indole;    epoxide;    solvent-free;   

DOI  :  10.1080/17518253.2012.666273

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

3-Alkylindole derivatives were produced by ring opening of epoxides in the presence of magnesium oxide nanoparticles as an efficient catalyst. Solvent-free conditions, stoichiometric amounts of reactants, and improved reaction times and yields are the most important advantages of this method. MgO nanoparticles are synthesized successfully. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Brunauer- Emmet-Teller (BET) surface measurement were used to characterize the structure and morphology of the catalyst.

【 授权许可】

Unknown