An efficient and practical synthesis of 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazole using silica-supported sodium hydrogen sulfate as a heterogeneous catalyst

Green Chemistry Letters and Reviews

Atul Chaskar¹ 

关键词: heterogeneous catalysis;    silica-supported sodium hydrogen sulfate;    multicomponent reaction;    1-aryl-1H;    3H-thiazolo[3;    4-a]benzimidazoles;   

DOI  :  10.1080/17518253.2012.739209

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

Silica-supported sodium hydrogen sulfate (NaHSO4·SiO2) efficiently catalyzed the three-component reactions of o-phenylenediamine, 2-mercaptoacetic acid, and aromatic aldehydes, and it formed the corresponding 1-aryl-1H,3H-thiazolo[3,4-a]benzimidazole. The catalyst is inexpensive and eco-friendly and works under heterogeneous conditions.

【 授权许可】

Unknown