Valutazione Economica Dell'impatto Organizzativo di Differenti Tecniche di Ibridazione in Situ per la Determinazione Dello Stato di HER2 nel Carcinoma Alla Mammella:

Global & Regional Health Technology Assessment

RobertoRavasio¹ 

关键词: Cost;    FISH;    HER2;    Hybridization;    Pathology;   

DOI  :  10.5301/grhta.5000265

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

The cost of antibiotic therapy and antibiotic resistance for complicated intra-abdominal infections (cIAIs) and complicated urinary tract infections (cUTIs) in ItalyObjectiveHuman epidermal growth factor receptor 2 (HER2) status identification is established by immunohi-stochemistry and in situ hybridization (ISH). Silver in situ hybridization (SISH) is an alternative technique to the fluorescence in situ hybridization (FISH). The American Society of Clinical Oncology (ASCO) and College of American Pathologists (CAP) 2013 guidelines recommend both methods. The primary aim of this analysis is to evaluate the economical and organizational impact of adopting FISH or SISH methods for HER2 testing.MethodsWe conducted an analysis to evaluate costs, staff times (laboratory working hours) and laboratory-space to process a sample using the manual method (FISH) compared to the automated system (SISH). The analysis was performed from the pathology laboratory perspective. We analysed the complete workflow (laboratory...

【 授权许可】

CC BY