Parasite | |
Comparative acaricidal efficacy of the topically applied combinations fipronil/(S)-methoprene, permethrin/imidacloprid and metaflumizone/ amitraz against Dermacentor reticulatus, the European dog tick (ornate dog tick, Fabricius, 1794) in dogs | |
and B. Gale1  M. Murphy1  T. Chester3  M. Polmeier2  C. Manavella2  E. Tielemans2  | |
[1] Charles River Laboratories, Preclinical Services Ireland Ltd, Glenamoy, Co. Mayo,Ireland;Merial S.A.S., Centre de Recherche de Saint-Vulbas, PIPA,Allée des Cyprès,01150 Saint-Vulbas,France;Merial Limited,3239 Satellite Blvd,Duluth,GA 30096-4640,USA | |
关键词: experimental infestation; amitraz; metaflumizone; permethrin; imidacloprid; (S)-methoprene; fipronil; efficacy; dog; Dermacentor reticulatus; tick; | |
Others : 808306 DOI : doi:10.1051/parasite/2010174343 |
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received in 2010-07-13, accepted in 2010-08-16, 发布年份 2010 | |
【 摘 要 】
The acaricidal efficacy against Dermacentor reticulatus in dogs of the commercial topical combinations fipronil/(S)-methoprene (FRONTLINE Combo® spot-on dog), imidacloprid/permethrin (Advantix®) and metaflumizone/amitraz (ProMeris Duo®) was evaluated and compared. Three treatment groups and one untreated control group of six adult Beagle dogs each were randomly formed. Each treatment was administered topically once on Day-0, according to the recommended label dose and instructions for use. All dogs were infested weekly with approximately 50 adult unfed D. reticulatus over a period of seven weeks. Ticks were removed and counted approximately 48 hours after each infestation. The percent reduction in numbers of ticks for fipronil/(S)-methoprene was ≥ 97 % compared to untreated controls for all seven weekly infestations. The percent reductions for imidacloprid/permethrin and metaflumizone/amitraz were satisfactory initially but fell and stayed below 90 % after three weeks. From the third week onwards, fipronil/(S)-methoprene treated dogs had significantly fewer ticks than imidacloprid/ permethrin or metaflumizone/amitraz treated dogs (p < 0.05).
【 授权许可】
© PRINCEPS Editions, Paris, 2010
【 预 览 】
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