Comparative acaricidal efficacy of the topically applied combinations fipronil/(S)-methoprene, permethrin/imidacloprid and metaflumizone/ amitraz against Dermacentor reticulatus, the European dog tick (ornate dog tick, Fabricius, 1794) in dogs

Parasite

and B. Gale¹  M. Murphy¹  T. Chester³  M. Polmeier²  C. Manavella²  E. Tielemans² 

[1] Charles River Laboratories, Preclinical Services Ireland Ltd, Glenamoy, Co. Mayo,Ireland;Merial S.A.S., Centre de Recherche de Saint-Vulbas, PIPA,Allée des Cyprès,01150 Saint-Vulbas,France;Merial Limited,3239 Satellite Blvd,Duluth,GA 30096-4640,USA

关键词: experimental infestation;    amitraz;    metaflumizone;    permethrin;    imidacloprid;    (S)-methoprene;    fipronil;    efficacy;    dog;    Dermacentor reticulatus;    tick;   

Others  :  808306
DOI  :  doi:10.1051/parasite/2010174343

 received in 2010-07-13, accepted in 2010-08-16,  发布年份 2010

【 摘 要 】

The acaricidal efficacy against Dermacentor reticulatus in dogs of the commercial topical combinations fipronil/(S)-methoprene (FRONTLINE Combo® spot-on dog), imidacloprid/permethrin (Advantix®) and metaflumizone/amitraz (ProMeris Duo®) was evaluated and compared. Three treatment groups and one untreated control group of six adult Beagle dogs each were randomly formed. Each treatment was administered topically once on Day-0, according to the recommended label dose and instructions for use. All dogs were infested weekly with approximately 50 adult unfed D. reticulatus over a period of seven weeks. Ticks were removed and counted approximately 48 hours after each infestation. The percent reduction in numbers of ticks for fipronil/(S)-methoprene was ≥ 97 % compared to untreated controls for all seven weekly infestations. The percent reductions for imidacloprid/permethrin and metaflumizone/amitraz were satisfactory initially but fell and stayed below 90 % after three weeks. From the third week onwards, fipronil/(S)-methoprene treated dogs had significantly fewer ticks than imidacloprid/ permethrin or metaflumizone/amitraz treated dogs (p < 0.05).

【 授权许可】

   
© PRINCEPS Editions, Paris, 2010