GMS German Medical Science — an Interdisciplinary Journal | |
Water, electrolytes, vitamins and trace elements – Guidelines on Parenteral Nutrition, Chapter 7Wasser, Elektrolyte, Vitamine und Spurenelemente – Leitlinie Parenterale Ernährung, Kapitel 7 | |
A. Muehlhoefer1  H. J. Boehles2  S. C. Bischoff3  H. K. Biesalski4  | |
[1] Dept. of Internal Medicine, Gastroenterology, Hepatology and Infectiology, St. Catharine's Hospital, Stuttgart, Germany;Dept. of Paediatrics, JohannWolfgangGoethe University of Frankfurt, Germany;Dept Nutritional Medicine and Prevention, University StuttgartHohenheim, Germany;Institute for Biochemistry und Nutrition Science, University of StuttgartHohenheim, Germany | |
关键词: vitamins; selenium; zinc; trace elements; fluid intake; | |
Others : 869111 | |
实施日期:2009-01-14,发布日期:2009-11-18 | |
【 摘 要 】
A close cooperation between medical teams is necessary when calculating the fluid intake of parenterally fed patients. Fluids supplied parenterally, orally and enterally, other infusions, and additional fluid losses (e.g. diarrhea) must be considered. Targeted diagnostic monitoring (volume status) is required in patients with disturbed water or electrolyte balance. Fluid requirements of adults with normal hydration status is approximately 30–40 ml/kg body weight/d, but fluid needs usually increase during fever. Serum electrolyte concentrations should be determined prior to PN, and patients with normal fluid and electrolyte balance should receive intakes follwing standard recommendations with PN. Additional requirements should usually be administered via separate infusion pumps. Concentrated potassium (1 mval/ml) or 20% NaCl solutions should be infused via a central venous catheter. Electrolyte intake should be adjusted according to the results of regular laboratory analyses. Individual determination of electrolyte intake is required when electrolyte balance is initially altered (e.g. due to chronic diarrhea, recurring vomiting, renal insufficiency etc.). Vitamins and trace elements should be generally substituted in PN, unless there are contraindications. The supplementation of vitamins and trace elements is obligatory after a PN of >1 week. A standard dosage of vitamins and trace elements based on current dietary reference intakes for oral feeding is generally recommended unless certain clinical situations require other intakes.
【 授权许可】
© 2009 Biesalski et al.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.
【 预 览 】
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【 参考文献 】
- [1]ASPEN Board of Directors and the Clinical Guidelines Task Force. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. JPEN J Parenter Enteral Nutr. 2002;26(1 Suppl):1SA-138SA.
- [2]Bischoff SC, Ockenga J, Manns MP. Künstliche Ernährung in der internistischen Intensivmedizin Chancen und Probleme [Artificial nutrition in intensive internal medicine. Chances and problems]. Internist (Berl). 2000;41(10):1041-61. DOI: 10.1007/s001080050663
- [3]Deutsche Gesellschaft für Ernährung. Referenzwerte für die Nährstoffzufuhr [Reference Values for Nutrient Intake]. Frankfurt am Main: Umschau-Braus-Verl.; 2000.
- [4]Filston HC. Fluid and electrolyte management in the pediatric surgical patient. Surg Clin North Am. 1992;72(6):1189-205.
- [5]Koretz RL, Lipman TO, Klein S. AGA technical review on parenteral nutrition. Gastroenterology. 2001;121:970-1001. DOI: 10.1016/S0016-5085(01)92000-1
- [6]Rose B, Post T. Clinical Physiology of acid-base and electrolyte disorders. New York: McGraw-Hill; 2001.
- [7]Food and Drug Administration (FDA). Parenteral Multivitamin Products; Drugs for Human Use; Drug Efficacy Study Implementation; Amendment. Federal Register. 2000;65:21200-1.
- [8]Kelly DG. Guidelines and available products for parenteral vitamins and trace elements. JPEN J Parenter Enteral Nutr. 2002;26(5 Suppl):S34-6.
- [9]Davis AT, Franz FP, Courtnay DA, Ullrey DE, Scholten DJ, Dean RE. Plasma vitamin and mineral status in home parenteral nutrition patients. JPEN J Parenter Enteral Nutr. 1987;11(5):480-5. DOI: 10.1177/0148607187011005480
- [10]Labadarios D, O'Keefe SJ, Dicker J, Van Stuijvenberg L, Visser L, Louw ME, Shephard GS. Plasma vitamin levels in patients on prolonged total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1988;12(2):205-11. DOI: 10.1177/0148607188012002205
- [11]Marinier E, Gorski AM, de Courcy GP, Criqui C, Bunodiere M, Christides JP, Causse MB, Brion F, Ricour C, Navarro J. Blood levels of water-soluble vitamins in pediatric patients on total parenteral nutrition using a multiple vitamin preparation. JPEN J Parenter Enteral Nutr. 1989;13(2):176-84. DOI: 10.1177/0148607189013002176
- [12]Silvers KM, Sluis KB, Darlow BA, McGill F, Stocker R, Winterbourn CC. Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid. Acta Paediatr. 2001;90(3):242-9. DOI: 10.1080/080352501300067433
- [13]Guidelines for essential trace element preparations for parenteral use. A statement by an expert panel. AMA Department of Foods and Nutrition. JAMA. 1979;241(19):2051-4.
- [14]Greene HL, Hambidge KM, Schanler R, Tsang RC. Guidelines for the use of vitamins, trace elements, calcium, magnesium, and phosphorus in infants and children receiving total parenteral nutrition: report of the Subcommittee on Pediatric Parenteral Nutrient Requirements from the Committee on Clinical Practice Issues of the American Society for Clinical Nutrition. Am J Clin Nutr. 1988;48(5):1324-42.
- [15]Mikalunas V, Fitzgerald K, Rubin H, McCarthy R, Craig RM. Abnormal vitamin levels in patients receiving home total parenteral nutrition. J Clin Gastroenterol. 2001;33(5):393-6. DOI: 10.1097/00004836-200111000-00010
- [16]Steephen AC, Traber MG, Ito Y, Lewis LH, Kayden HJ, Shike M. Vitamin E status of patients receiving long-term parenteral nutrition: is vitamin E supplementation adequate? JPEN J Parenter Enteral Nutr. 1991;15(6):647-52. DOI: 10.1177/0148607191015006647
- [17]Smith JL, Canham JE, Kirkland WD, Wells PA. Effect of Intralipid, amino acids, container, temperature, and duration of storage on vitamin stability in total parenteral nutrition admixtures. JPEN J Parenter Enteral Nutr. 1988;12(5):478-83. DOI: 10.1177/0148607188012005478
- [18]Jonas CR, Puckett AB, Jones DP, Griffith DP, Szeszycki EE, Bergman GF, Furr CE, Tyre C, Carlson JL, Galloway JR, Blumberg JB, Ziegler TR. Plasma antioxidant status after high-dose chemotherapy: a randomized trial of parenteral nutrition in bone marrow transplantation patients. Am J Clin Nutr. 2000;72(1):181-9.
- [19]Vollbracht C, McGregor P. Vitamin C - ein für die Intensivmedizin essenzieller Mikronährstoff [Vitamin C - an essential micro nutrient for the intensive care medicine]. In: Hartig W, Biesalski HK, Druml W, Fuerst P, Weimann A, Hrsg. Ernaehrung und Infusionstherapie. Standards fuer Klinik, Intensivtherapie und Ambulanz. Stuttgart: Thieme; 2004. p. 37-48.
- [20]Berger MM, Chioléro RL. Key vitamins and trace elements in the critically ill. Nestle Nutr Workshop Ser Clin Perform Programme. 2003;8:99-111. DOI: 10.1159/000072750
- [21]Nathens AB, Neff MJ, Jurkovich GJ, Klotz P, Farver K, Ruzinski JT, Radella F, Garcia I, Maier RV. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg. 2002;236(6):814-22. DOI: 10.1097/00000658-200212000-00014
- [22]Young B, Ott L, Kasarskis E, Rapp R, Moles K, Dempsey RJ, Tibbs PA, Kryscio R, McClain C. Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. J Neurotrauma. 1996;13(1):25-34. DOI: 10.1089/neu.1996.13.25
- [23]Angstwurm MW, Schottdorf J, Schopohl J, Gaertner R. Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome. Crit Care Med. 1999;27(9):1807-13. DOI: 10.1097/00003246-199909000-00017
- [24]Berger MM, Reymond MJ, Shenkin A, Rey F, Wardle C, Cayeux C, Schindler C, Chioléro RL. Influence of selenium supplements on the post-traumatic alterations of the thyroid axis: a placebo-controlled trial. Intensive Care Med. 2001;27(1):91-100. DOI: 10.1007/s001340000757
- [25]Galley HF, Davies MJ, Webster NR. Ascorbyl radical formation in patients with sepsis: effect of ascorbate loading. Free Radic Biol Med. 1996;20(1):139-43. DOI: 10.1016/0891-5849(95)02022-5
- [26]Galley HF, Howdle PD, Walker BE, Webster NR. The effects of intravenous antioxidants in patients with septic shock. Free Radic Biol Med. 1997;23(5):768-74. DOI: 10.1016/S0891-5849(97)00059-2
- [27]Berger MM, Cavadini C, Chiolero R, Guinchard S, Krupp S, Dirren H. Influence of large intakes of trace elements on recovery after major burns. Nutrition. 1994;10(4):327-34.
- [28]Berger MM, Spertini F, Shenkin A, Wardle C, Wiesner L, Schindler C, Chiolero RL. Trace element supplementation modulates pulmonary infection rates after major burns: a double-blind, placebo-controlled trial. Am J Clin Nutr. 1998;68(2):365-71.
- [29]Bertin-Maghit M, Goudable J, Dalmas E, Steghens JP, Bouchard C, Gueugniaud PY, Petit P, Delafosse B. Time course of oxidative stress after major burns. Intensive Care Med. 2000;26(6):800-3. DOI: 10.1007/s001340051250
- [30]Ritter C, Andrades M, Guerreiro M, Zavaschi L, Gelain DP, Souza LF, Ribeiro CA, Clausell N, Menna-Barreto S, Moreira JC, Dal-Pizzol F. Plasma oxidative parameters and mortality in patients with severe burn injury. Intensive Care Med. 2003;29(8):1380-3. DOI: 10.1007/s00134-003-1833-9
- [31]Laurent T, Markert M, Feihl F, Schaller MD, Perret C. Oxidant-antioxidant balance in granulocytes during ARDS. Effect of N-acetylcysteine. Chest. 1996;109(1):163-6. DOI: 10.1378/chest.109.1.163
- [32]Cross JM, Donald AE, Nuttall SL, Deanfield JE, Woolfson RG, Macallister RJ. Vitamin C improves resistance but not conduit artery endothelial function in patients with chronic renal failure. Kidney Int. 2003;63(4):1433-42. DOI: 10.1046/j.1523-1755.2003.00852.x
- [33]Ambrose ML, Bowden SC, Whelan G. Working memory impairments in alcohol-dependent participants without clinical amnesia. Alcohol Clin Exp Res. 2001;25(2):185-91. DOI: 10.1111/j.1530-0277.2001.tb02197.x
- [34]Hung SC, Hung SH, Tarng DC, Yang WC, Chen TW, Huang TP. Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis. 2001;38(5):941-7. DOI: 10.1053/ajkd.2001.28578
- [35]Thomson AD, Cook CC, Touquet R, Henry JA; Royal College of Physicians, London. The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and Emergency Department. Alcohol Alcohol. 2002;37(6):513-21. DOI: 10.1093/alcalc/37.6.513