Ruminant self-medication against gastrointestinal nematodes: evidence, mechanism, and origins

Parasite

and John Glendinning²  Serge Y. Landau¹  Eugene D. Ungar¹  James Miller³  Juan J. Villalba⁴ 

[1] Department of Natural Resources, Institute of Plant Sciences, Agricultural Research Organization, the Volcani Center,Bet Dagan50250,Israel;Department of Biology, Barnard College, Columbia University,3009 Broadway,New York,NY,USA;Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University,70803Baton Rouge,USA;Department of Wildland Resources, Utah State University,5230 Old Main Hill,Logan,Utah84322-5230,USA

关键词: Learning;    Condensed tannins;    Foraging behavior;    Diet selection;   

Others  :  808294
DOI  :  doi:10.1051/parasite/2014032

 received in 2014-01-10, accepted in 2014-06-17,  发布年份 2014

【 摘 要 】

Gastrointestinal helminths challenge ruminants in ways that reduce their fitness. In turn, ruminants have evolved physiological and behavioral adaptations that counteract this challenge. Ruminants display anorexia and avoidance behaviors, which tend to reduce the incidence of parasitism. In addition, ruminants appear to learn to self-medicate against gastrointestinal parasites by increasing consumption of plant secondary compounds with antiparasitic actions. This selective feeding improves health and fitness. Here, we review the evidence for self-medication in ruminants, propose a hypothesis to explain self-medicative behaviors (based on post-ingestive consequences), and discuss mechanisms (e.g., enhanced neophilia, social transmission) that may underlie the ontogeny and spread of self-medicative behaviors in social groups. A better understanding of the mechanisms that underlie and trigger self-medication in parasitized animals will help scientists devise innovative and more sustainable management strategies for improving ruminant health and well-being.

【 授权许可】

   
© J.J. Villalba et al., published by EDP Sciences, 2014

【 图 表 】

Figure 1.

Figure 2.

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