期刊论文详细信息
GMS German Medical Science — an Interdisciplinary Journal
Intensive medicine – Guidelines on Parenteral Nutrition, Chapter 14Intensivmedizin – Leitlinie Parenterale Ernährung, Kapitel 14
K. W. Jauch2  W. Druml4  M. Adolph1  G. Kreymann3 
[1] Dept. of Anaesthesiology and Intensive Medicine, EberhardKarl University, Tuebingen, Germany;Dept. Surgery Grosshadern, University Hospital, Munich, Germany;Dept. of Medicine, University of Hamburg, Germany;Clinical Dept. of Nephrology and Dialysis, University of Vienna, Austria
关键词: intensive care;    sepsis;    critically ill;    substrate supply;   
Others  :  869123
实施日期:2009-01-14,发布日期:2009-11-18
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【 摘 要 】

In intensive care patients parenteral nutrition (PN) should not be carried out when adequate oral or enteral nutrition is possible. Critically ill patients without symptoms of malnutrition, who probably cannot be adequately nourished enterally for a period of <5 days, do not require full PN but should be given at least a basal supply of glucose. Critically ill patients should be nourished parenterally from the beginning of intensive care if they are unlikely to be adequately nourished orally or enterally even after 5–7 days. Critically ill and malnourished patients should, in addition to a possible partial enteral nutrition, be nourished parenterally. Energy supply should not be constant, but should be adapted to the stage, the disease has reached. Hyperalimentation should be avoided at an acute stage of disease in any case. Critically ill patients should be given, as PN, a mixture consisting of amino acids (between 0.8 and 1.5 g/kg/day), carbohydrates (around 60% of the non-protein energy) and fat (around 40% of the non-protein energy) as well as electrolytes and micronutrients.

【 授权许可】

   
© 2009 Kreymann et al.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

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【 参考文献 】
  • [1]Braunschweig CL, Levy P, Sheean PM, Wang X. Enteral compared with parenteral nutrition: a meta-analysis. Am J Clin Nutr. 2001;74(4):534-42.
  • [2]Bertolini G, Iapichino G, Radrizzani D, Facchini R, Simini B, Bruzzone P,Zanforlin G, Tognoni G. Early enteral immunonutrition in patients with severe sepsis: results of an interim analysis of a randomized multicentre clinical trial. Intensive Care Med. 2003;29(5):834-40.
  • [3]Woodcock NP, Zeigler D, Palmer MD, Buckley P, Mitchell CJ, MacFie J. Enteral versus parenteral nutrition: a pragmatic study. Nutrition. 2001;17(1):1-12. DOI: 10.1016/S0899-9007(00)00576-1 
  • [4]Sandström R, Drott C, Hyltander A, Arfvidsson B, Scherstén T, Wickström I, Lundholm K. The effect of postoperative intravenous feeding (TPN) on outcome following major surgery evaluated in a randomized study. Ann Surg. 1993;217(2):185-95.
  • [5]Tappy L, Schwarz JM, Schneiter P, Cayeux C, Revelly JP, Fagerquist CK, Jéquier E, Chioléro R. Effects of isoenergetic glucose-based or lipid-based parenteral nutrition on glucose metabolism, de novo lipogenesis, and respiratory gas exchanges in critically ill patients. Crit Care Med. 1998;26(5):860-7. DOI: 10.1097/00003246-199805000-00018 
  • [6]Battistella FD, Widergren JT, Anderson JT, Siepler JK, Weber JC, MacColl K. A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition. J Trauma. 1997;43(1):52-8. DOI: 10.1097/00005373-199707000-00013 
  • [7]Heyland DK, MacDonald S, Keefe L, Drover JW. Total parenteral nutrition in the critically ill patient: a meta-analysis. JAMA. 1998;280(23):2013-9. DOI: 10.1001/jama.280.23.2013 
  • [8]Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345(19):1359-67. DOI: 10.1056/NEJMoa011300 
  • [9]Finney SJ, Zekveld C, Elia A, Evans TW. Glucose control and mortality in critically ill patients. JAMA. 2003;290(15):2041-7. DOI: 10.1001/jama.290.15.2041 
  • [10]Van den Berghe G, Wouters PJ, Bouillon R, Weekers F, Verwaest C, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P. Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit Care Med. 2003;31(2):359-66. DOI: 10.1097/01.CCM.0000045568.12881.10 
  • [11]Serón Arbeloa C, Avellanas Chavala M, Homs Gimeno C, Larraz Vileta A, Laplaza Marín J, Puzo Foncillas J. [Evaluation of a high protein diet in critical care patients]. Nutr Hosp. 1999;14(5):203-9.
  • [12]Ishibashi N, Plank LD, Sando K, Hill GL. Optimal protein requirements during the first 2 weeks after the onset of critical illness. Crit Care Med. 1998;26(9):1529-35. DOI: 10.1097/00003246-199809000-00020 
  • [13]Van der Heijden A, Verbeek MJ, Schreurs VV, Akkermans LM, Vos A. [Effect of increasing protein ingestion on the nitrogen balance of mechanically ventilated critically ill patients receiving total parenteral nutrition]. Nutr Hosp. 1993;8(5):279-87.
  • [14]Larsson J, Lennmarken C, Mårtensson J, Sandstedt S, Vinnars E. Nitrogen requirements in severely injured patients. Br J Surg. 1990;77(4):413-6. DOI: 10.1002/bjs.1800770418 
  • [15]Wolfe RR, Goodenough RD, Burke JF, Wolfe MH. Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann Surg. 1983;197(2):163-71. DOI: 10.1097/00000658-198302000-00007 
  • [16]Schmitz JE, Lotz P, Ahnefeld FW, Grunert A. Protein and energy metabolism in intensive care patients. Infusionsther Klin Ernähr. 1981;8:158-162.
  • [17]Scheinkestel CD, Kar L, Marshall K, Bailey M, Davies A, Nyulasi I, Tuxen DV. Prospective randomized trial to assess caloric and protein needs of critically Ill, anuric, ventilated patients requiring continuous renal replacement therapy. Nutrition. 2003;19(11-12):909-16. DOI: 10.1016/S0899-9007(03)00175-8 
  • [18]Hoffer LJ. Protein and energy provision in critical illness. Am J Clin Nutr. 2003;78(5):906-11.
  • [19]Novak F, Heyland DK, Avenell A, Drover JW, Su X. Glutamine supplementation in serious illness: a systematic review of the evidence. Crit Care Med. 2002;30(9):2022-9. DOI: 10.1097/00003246-200209000-00011 
  • [20]Wischmeyer PE, Lynch J, Liedel J, Wolfson R, Riehm J, Gottlieb L, Kahana M. Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control. Crit Care Med. 2001;29(11):2075-80. DOI: 10.1097/00003246-200111000-00006 
  • [21]Fuentes-Orozco C, Anaya-Prado R, González-Ojeda A, Arenas-Márquez H, Cabrera-Pivaral C, Cervantes-Guevara G, Barrera-Zepeda LM. L-alanyl-L-glutamine-supplemented parenteral nutrition improves infectious morbidity in secondary peritonitis. Clin Nutr. 2004;23(1):13-21. DOI: 10.1016/S0261-5614(03)00055-4 
  • [22]Goeters C, Wenn A, Mertes N, Wempe C, Van Aken H, Stehle P, Bone HG. Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients. Crit Care Med. 2002;30(9):2032-7. DOI: 10.1097/00003246-200209000-00013 
  • [23]Griffiths RD, Jones C, Palmer TE. Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutrition. Nutrition. 1997;13(4):295-302.
  • [24]Powell-Tuck J, Jamieson CP, Bettany GE, Obeid O, Fawcett HV, Archer C, Murphy DL. A double blind, randomised, controlled trial of glutamine supplementation in parenteral nutrition. Gut. 1999;45(1):82-8.
  • [25]Freund HR, Hanani M. The metabolic role of branched-chain amino acids. Nutrition. 2002;18(3):287-8. DOI: 10.1016/S0899-9007(01)00740-7 
  • [26]García-de-Lorenzo A, Ortíz-Leyba C, Planas M, Montejo JC, Núñez R, Ordóñez FJ, Aragón C, Jiménez FJ. Parenteral administration of different amounts of branch-chain amino acids in septic patients: clinical and metabolic aspects. Crit Care Med. 1997;25(3):418-24. DOI: 10.1097/00003246-199703000-00008 
  • [27]Wang XY, Li N, Gu J, Li WQ, Li JS. The effects of the formula of amino acids enriched BCAA on nutritional support in traumatic patients. World J Gastroenterol. 2003;9(3):599-602.
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