Share of afghanistan populace in hepatitis B and hepatitis C infection's pool: is it worthwhile?

Virology Journal

Sobia Attaullah¹  Sanaullah Khan² 

[1] Department of Zoology, Islamia College Peshawar (A Public Sector University), University Campus, Jamrod Road, Peshawar 25120, Khyber Pakhtunkhwa Pakistan;Molecular Parasitology and Virology Laboratory, Department of Zoology, Kohat University of Science and Technology, Kohat 26000, Khyber Pakhtunkhwa Pakistan

关键词: Afghanistan;    Risk groups;    Risk behaviours;    Epidemiology;    Hepatitis C virus;    Hepatitis B virus;   

Others  :  1156721
DOI  :  10.1186/1743-422X-8-216

 received in 2011-04-17, accepted in 2011-05-11,  发布年份 2011

【 摘 要 】

There is a notable dearth of data about Hepatitis B Virus (HBV) and Hepatitis C Virus(HCV) prevalence in Afghanistan. Awareness program and research capacity in the field of hepatitis are very limited in Afghanistan. Number of vulnerabilities and patterns of risk behaviors signal the need to take action now.

Thirty one studies dating from October 2003 to 2011 were included, consisting the data of 1,32,981 individuals for HBV and 1,32,500 individuals for HCV. Percentage prevalence was 1.9% for HBV and 1.1% for HCV in all available Afghanistan population. Most at risk population to hepatitis include injecting drug users who share needles and female sex workers, while truck drivers, prisoners and homosexual men needs attention, as their statistical figure are missing. Data suggests that high incidence of intravenous drug use, sexual activities, unsafe blood transfusion procedures and mobility are major risk factors for hepatitis transmission.

This review is based on analysis of the limited available data in Afghanistan. Although there are many underlying vulnerability factors, it appears that Afghanistan remains at an early epidemic phase. Further research is required to determine the seroprevalence and prevalent genotype(s) of HBV and HCV in all provinces in Afghanistan. This article provides some key insights into the potential and likely future transmission dynamics of Hepatitis which will serve as a guide in the identification of priority areas in term of high risk groups and risk behaviours in the country and will assist to develop urgent strategic plans to combat the future burden of Hepatitis in Afghanistan.

【 授权许可】

   
2011 Khan and Attaullah; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Krasteva A, Panov VI, Garova M, Velikova R, Kisselova A, Krastev Z: Hepatitis B and C in Dentistry. Journal of IMAB - Annual Proceeding 2008, 14(book 2):38-40. (Scientific Papers)
• [2]Singhal V, Bora D, Singh S: Hepatitis B in health care workers: Indian scenario. Journal of Laboratory Physians 2009, 1(2):41-48.
• [3]Mukhopadhya A: Hepatitis C in India. J Biosc 2008, 33:465-473.
• [4]United Nations General Assembly Special Session on HIV/AIDS, Country Progress Report (Reporting Period January 2008 to December 2009) Islamic Republic of Afghanistan; 2010.
• [5]UNICEF Report, Statistics of Afghanistan 2010.
• [6]Afghanistan National Strategic Framework for HIV/AIDS: National HIV/AIDS and STI Control Programme (2006-2010), Working Draft 05/07/08, National AIDS Control Program. Ministry of Public Health, Islamic Republic of Afghanistan; 2008.
• [7]Zafar T, Brahmbhatt H, Imam G, Hassan S, Strathdee S: Epidemiology and Social Science HIV Knowledge and Risk Behaviors among Pakistani and Afghani Drug Users in Quetta, Pakistan. Journal of Acquired Immune Deficiency Syndromes 2003, 32(4):394-398.
• [8]Todd CS, Ahmadzai M, Atiqzai F, Miller S, Smith JM, Ghazanfar SA, Strathdee SA: Seroprevalence and correlates of HIV, syphilis, and hepatitis B and C virus among intrapartum patients in Kabul, Afghanistan. BMC Infect Dis 2008, 17(8):119.
• [9]Quddus A, Luby SP, Jamal Z, Jafard T: Prevalence of hepatitis B among Afghan refugees living in Balochistan, Pakistan. International Journal of Infectious Diseases 2006, 10(3):242-247.
• [10]Todd CS, Abed AMS, Strathdee SA, Scott PT, Botros BA, Safi N, Earhart KC: Prevalence of HIV, hepatitis C, hepatitis B, and associated risk behaviors among injection drug users in Kabul, Afghanistan. Emerg Infect Dis 2007, 13(9):1327-31.
• [11]Nasir A, Todd CS, Stanekzai MR, Bautista CT, Botros BA, Scott PT, Kim JH, Strathdee SA, Tjaden J: Prevalence of HIV, hepatitis B and hepatitis C and associated risk behaviours amongst injecting drug users in three Afghan cities. Int J Drug Policy 2011, 22(2):145-52.
• [12]Nasir A, Todd CS, Stanekzai MR, Bautista CT, Botros BA, Scott PT, Kim JH, Strathdee SA, Tjaden J: Implications of hepatitis C viremia vs. antibody alone on transmission among male injecting drug users in three Afghan cities. Int J Infect Dis 2011, 15(3):e201-5.
• [13]Todd CS, Nasir A, Stanekzai MR, Bautista CT, Botros BA, Scott PT, Strathdee SA, Tjaden J: HIV, hepatitis B, and hepatitis C prevalence and associated risk behaviors among female sex workers in three Afghan cities. AIDS 2010, 24:S69-S75.
• [14]Central Blood Bank: Report of testing of Blood donors from March-December, 2006. Ministry of Public Health Afghanistan;
• [15]Ali SA, Donahue RMJ, Qureshi H, Vermund SH: Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors. Int J Infect Dis 2009, 13(1):9-19.
• [16]Kitt MM, Khalid G, Rahimi S, McCarthy BJ: An Occupational Health Services Initiative at a Women's Hospital in Kabul. Afghanistan Public Health Rep 2006, 121(6):650-657.
• [17]Salehi AS, Garner P: Occupational injury history and universal precautions awareness: a survey in Kabul hospital staff. BMC Infect Dis 2010, 10:19. BioMed Central Full Text
• [18]Rein DB, Lesesne SB, O'Fallon A, Weinbaum CM: Prevalence of Hepatitis B Surface Antigen Among Refugees Entering the United States Between 2006 and 2008. Hepatology 2009, 51:1-4.
• [19]Pourkarim MR, Zandi K, Davani NA, Pourkarim HR, Amini-Bavil-Olyaee S: An aberrant high prevalence of hepatitis B infection among Afghans residing in one of the Bushehr refugee camps (Dalaki camp) in the southwest of Iran. Int j Infect Dis 2008, 12(1):101-2.
• [20]Wright TL: Introduction to Chronic Hepatitis B Infection. Am J Gastroenterol 101:S1-S6.
• [21]Baig S, Siddiqui A, Chakravarty R, Moatter T: Hepatitis B virus subgenotypes D1 and D3 are prevalent in Pakistan. BMC Res Notes 2009, 4(2):1.
• [22]Amini-Bavil-Olyaee S, Alavian SM, Adeli A, Sarrami-Forooshani R, Sabahi F: Hepatitis B virus genotyping, core promoter and precore/core mutations among afghan patients infected with hepatitis B: a preliminary report. Journal of Medical Virology 2006, 78(3):358-364.
• [23]Human Development Report 2009: Foreword Overcoming barriers: Human mobility and development United Nations Development Programm (UNDP 2009). Retrieved 14/11/2010
• [24]South Asia Human Development Sector, Mapping and Situation Assessment of Key Populations at High Risk of HIV in Three Cities of Afghanistan. Report No. 23 SAR AIDS (South Asia Regional AIDS), Human Development Sector South Asia Region;
• [25]Bautista CA, Todd CS, Abed AMS, Botros BA, Strathdee SA, Earhart KC, Safi N, Scott PT: Effects of duration of injection drug use and age at first injection on HCV among IDU in Kabul. Afghanistan Journal of Public Health 2010, 32(3):336-341.
• [26]Alam S, Ahmad N, Khan M, Mustafa G, Al Mamun A, Mashud G: Seroprevalence of Hepatitis C Virus Infection among Health Care Workers. J Bangladesh College of Physicians and Surgeons 2007, 25(3):126-129.
• [27]Alavian SM, Fallahian F, Lankaran KB: Epidemiology of Hepatitis C in Iran and the World. Shiraz E-Medical Journal 2007, 16(4):403-406.
• [28]Afghanistan: Female Prisoners and their Social Reintegration UNITED NATIONS New York, UNITED NATIONS OFFICE ON DRUGS AND CRIME Vienna Project: AFG/S47--Developing Post-Release Opportunities or Women and Girl Prisoners. 2007.
• [29]Todd CS, Nasir A, Stanekzai MR, Abed AMS, Strathdee SA, Bautista CT, Scott PT, Botros BA, Tjaden J: Prevalence and correlates of syphilis and condom use among male injection drug users in four Afghan cities. Sexually Transmitted Diseases 2010, 37(11):719-25.
• [30]Wallace MR, Hale BR, Utz GC, Olson PK, Earhart KC, Thornton SA, Hyams KC: Endemic Infectious Diseases of Afghanistan. Oxford Journals Medicine Clinical Infectious Diseases 2002, 34(5):S171-S207.
• [31]Hugo G: Indonesia internal and international population mobility: implication for the spread of HIV/AIDS. HUMAN DEVELOPENT REPORT 2009 South East Asia HIV and Development Office ILO, Indonesia, UNAIDS Indonesia; 2001.
• [32]Alavi M, Behdad F: Seroprevalence Study of Hepatitis C and Hepatitis B Virus among Hospitalized Intravenous Drug Users in Ahvaz, Iran (2002-2006). Hepatitis Monthly 2010, 10(2):101-104.
• [33]Todd CS, Ahmadzai M, Atiqzai F, Smith JM, Miller S, Azfar P, Siddiqui H, Ghazanfar SA, Strathdee SA: Prevalence and correlates of HIV, syphilis, and hepatitis knowledge among intrapartum patients and health care providers in Kabul, Afghanistan. AIDS Care 2009, 21(1):109-17.
• [34]Todd CS, Ahmadzai M, Smith JM, Siddiqui H, Ghazanfar SA, Strathdee SA: Attitudes and practices of obstetric care providers in Kabul, Afghanistan regarding antenatal testing for sexually transmitted infection. J Obstet Gynecol Neonatal Nurs 2008, 37(5):607-15.