Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, China

Substance Abuse Treatment, Prevention, and Policy

Wenhua Zhou²  Yahai Zhang²  Xiuyi Lv¹  Longhui Li²  Nicholas Bartlett³  Yu Liu¹ 

[1] School of Medicine, Ningbo University, 818 Fenghua Street, Jiangbei District, Ningbo, Zhejiang 315211, China;Laboratory of Behavioral Neuroscience Ningbo Addiction Treatment and Research Center, 42 Xibei Road, Haishu District, Ningbo, Zhejiang 315010, China;Department of Anthropology, History and Social Medicine, University of California, San Francisco, 55 Laguna Street, San Francisco, CA 94102-6232, USA

关键词: Peer education compulsory detoxification centers;    Naloxone;    Opiate addiction;    Overdose prevention;   

Others  :  834535
DOI  :  10.1186/1747-597X-7-6

 received in 2011-11-07, accepted in 2012-02-08,  发布年份 2012

【 摘 要 】

Background

To date there has been limited research on both the prevalence of overdose and drug user knowledge about overdose prevention and response methods in China. In addition, there has been no effort to integrate naloxone information and distribution into pre-release services for drug users detained in isolated compulsory detoxification facilities in China.

Methods

The authors conducted a survey of 279 heroin users in isolated compulsory detoxification centers in Ningbo, China in an attempt to evaluate the possibility of conducting prelease peer naloxone programs in Ningbo isolated compulsory detoxification centers. Respondents' demographic background, history of heroin overdoses, and attitudes/knowledge about overdose prevention and response were collected.

Results

While drug users in Ningbo's compulsory detoxification centers have limited understandings of how to effectively respond to overdoses, they expressed concern about the possibility of overdose, interest in participating in overdose prevention and response programs, and a willingness to help their peers. In general, there was no significant difference in history and attitudes/knowledge of overdose between male and female participants.

Conclusion

Based on the findings of this research, our survey provides preliminary evidence that detained drug users have considerable interest in overdose prevention and response information and willingness to help peers. However, drug users in Ningbo isolated compulsory detoxification centers currently have limited understandings of effective ways of helping to prevent overdose deaths.

【 授权许可】

   
2012 Liu et al; BioMed Central Ltd.

【 参考文献 】

• [1]Bernstein KT, Bucciarelli A, Piper TM, Gross C, Tardiff K, Galea S: Cocaine- and opiate-related fatal overdose in New York City, 1990-2000. BMC Publ Health 2007, 7:31. BioMed Central Full Text
• [2]Davidson PJ, McLean RL, Kral AH, Gleghorn AA, Edlin BR, Moss AR: Fatal heroin-related overdose in San Francisco, 1997-2000: a case for targeted intervention. J Urban Health 2003, 80(2):261.
• [3]Engstrom A, Adamsson C, Allebeck P, Rydberg U: Mortality in patients with substance abuse: a follow-up in Stockholm County, 1973-1984. Intern J Addict 1991, 26(1):91.
• [4]Hser YI, Hoffman V, Grella CE, Anglin MD: A 33-year follow-up of narcotics addicts. Arch Gen Psychiatry 2001, 58(5):503.
• [5]Sergeev B, Karpets A, Sarang A, Tikhonov M: Prevalence and circumstances of opiate overdose among injection drug users in the Russian Federation. Journal of Urban Health 2003, 80(2):212.
• [6]Green TC, McGowan SK, Yokell MA, Pouget ER, Rich JD: HIV infection and risk of overdose: a systematic review and meta-analysis. AIDS 2011, in press.
• [7]Chamberlain JM, Klein BL: A comprehensive review of naloxone for the emergency physician. Am J Emerg Med 1994, 12(6):650.
• [8]Kim D, Irwin KS, Khoshnood K: Expanded access to naloxone: options for critical response to the epidemic of opioid overdose mortality. Am J Public Health 2009, 99(3):402.
• [9]Maxwell S, Bigg D, Stanczykiewicz K, Carlberg-Racich S: Prescribing naloxone to actively injecting heroin users: a program to reduce heroin overdose deaths. J Addict Dis 2006, 25(3):89.
• [10]Seal KH, Thawley R, Gee L, Bamberger J, Kral AH, Ciccarone D: Naloxone distribution and cardiopulmonary resuscitation training for injection drug users to prevent heroin overdose death: a pilot intervention study. J Urban Health 2005, 82(2):303.
• [11]Buajordet I, Naess AC, Jacobsen D, Brørs O: Adverse events after naloxone treatment of episodes of suspected acute opioid overdose. Eur J Emerg Med 2004, 11(1):19.
• [12]Coffin P, Sherman S, Curtis M: Underestimated and overlooked: a global review of drug overdose and overdose prevention. In Global State of Harm Reduction 2010: Key Issues for Broadening the Response. Edited by Cooke K. International Harm Reduction Association; 113-119.
• [13]Darke S, Williamson A, Ross J, Mills KL, Havard A, Teesson M: Patterns of nonfatal heroin overdose over a 3-year period: findings from the Australian treatment outcome study. J Urban Health 2007, 84(2):283.
• [14]Rosenberg H, Melville J, McLean PC: Acceptability and availability of pharmacological interventions for substance misuse by British NHS treatment services. Addiction 2002, 97(1):59.
• [15]Thurmond P, Bowman S: An overview of heroin overdose prevention in the northeast: new opportunities. Medicine & Health Rhode Island 2007, 90(5):148.
• [16]Wright H, Oldham N, Francis K, Jones L: Homeless drug users' awareness and risk perception of peer "Take Home Naloxone" use - a qualitative study. Subst Abus Treat Prev Policy 2006, 1:28. BioMed Central Full Text
• [17]Lenton SR, Dietze PM, Degenhardt L, Darke S, Butler TG: Naloxone for administration by peers in cases of heroin overdose. Med J Australia 2009, 191(8):469.
• [18]Piper TM, Rudenstine S, Stancliff S, Sherman S, Nandi V, Clear A: Overdose prevention for injection drug users: lessons learned from naloxone training and distribution programs in New York City. Harm Reduct J 2007, 4:3. BioMed Central Full Text
• [19]Sherman SG, Gann DS, Tobin KE, Latkin CA, Welsh C, Bielenson P: "The life they save may be mine": diffusion of overdose prevention information from a city sponsored programme. Int J Drug Policy 2009, 20(2):137.
• [20]Tobin KE, Sherman SG, Beilenson P, Welsh C, Latkin CA: Evaluation of the Staying Alive programme: training injection drug users to properly administer naloxone and save lives. Int J Drug Policy 2009, 20(2):131.
• [21]Wagner KD, Valente TW, Casanova M, Partovi SM, Mendenhall BM, Hundley JH: Evaluation of an overdose prevention and response training programme for injection drug users in the Skid Row area of Los Angeles, CA. Int J Drug Policy 2010, 21(3):186.
• [22]UNAIDS China Country Office: Compulsory and Isolated Drug Rehabilitation Center in China. Situation and opportunities. Presentation at the UNODC & UNAIDS Informal Consultation on Compulsory Centres for Drug Users. Bangkok, Thailand; 2010.
• [23]Bartlett N, Xin D, Zhang H, Huang K: A qualitative evaluation of a peer-implemented overdose response pilot project in Gejiu, China. Int J Drug Policy 2011, 22(4):301.
• [24]Yin L, Qin GM, Ruan YH, Qian HZ, Hao C, Xie LZ, Chen KL, Zhang YF, Xia YW, Wu JL, Lai SH, Shao YM: Nonfatal overdose among heroin users in southwestern China. American J Drug Alcohol Abuse 2007, 38:505.
• [25]Zhang L, Ruan YH, Jiang ZQ, Yang ZN, Liu SZ, Zhou F, He YX, Yin L, Qin GM, Shao YM: An 1-year prospective cohort study on mortality of injecting drug users. Chinese J Epidemiol 2005, 26:190.
• [26]Zhu Y, Yin L, Ruan Y, Hao C, Yao H, Yang X, Bian K, Liu L, Feng C, Qin G, Shao YM: A 3-Year Prospective Cohort Study on Mortality among Injecting Drug Users in Xichang County (in Chinese). Chinese J Nat Med 2006, 8:170-174.
• [27]Lu L, Fang Y, Wang X: Drug Abuse in China: Past Present and Future. Cell Mol Neurobiol 2008, 28:479.
• [28]Annual Report on drug Control in China, 2010 Office of China National Narcotic Control Commission 2010.
• [29]Sun B, Ye Y, Qin L: An analysis of relapse factors of 615 heroin addicts. Chinese Journal of Drug Dependence 2001, 10(3):214-216.
• [30]Zhao M, Hao W, yang D, Zhang YL, Li L: A prospective study of factors related to relapse in heroin addicts. Chinese Journal of Drug Dependence 2001, 9(2):81-84.
• [31]Bird SM, Hutchinson SJ: Male drugs-related deaths in the fortnight after release from prison: Scotland, 1996-99. Addiction 2003, 98(2):185.
• [32]Joukamaa M: The mortality of released Finnish prisoners; a 7 year follow-up study of the WATTU project. Forensic Sci Int 1998, 96(1):11.
• [33]Seaman SR, Brettle RP, Gore SM: Mortality from overdose among injecting drug users recently released from prison: database linkage study. BMJ 1998, 316(7129):426.
• [34]Verger P, Rotily M, Prudhomme J, Bird S: High mortality rates among inmates during the year following their discharge from a French prison. J Forensic Sci 2003, 48(3):614.
• [35]Wakeman SE, Bowman SE, McKenzie M, Jeronimo A, Rich JD: Preventing death among the recently incarcerated: an argument for naloxone prescription before release. J Addict Dis 2009, 28(2):124.
• [36]Prisons and the Health: Key Recommendations. WHO; 2010.
• [37]Curtis M, Guterman L: Overdose Prevention and Response: A Guide for People who use Drugs and Harm Reduction Staff in Eastern Europe and Central Asia. New York: Open Society Institute;
• [38]Lagu T, Anderson BJ, Stein M: Overdoses among friends: drug users are willing to administer naloxone to others. J Subst Abus Treat 2006, 30(2):129.
• [39]Strang J, Powis B, Best D, Vingoe L, Griffiths P, Taylor C: Preventing opiate overdose fatalities with take-home naloxone: pre-launch study of possible impact and acceptability. Addiction 1999, 94(2):199.
• [40]Seal KH, Kral AH, Gee L, Moore LD, Bluthenthal RN, Lorvick J: Predictors and prevention of nonfatal overdose among street-recruited injection heroin users in the San Francisco Bay Area, 1998-1999. Am J Public Health 2001, 91(11):1842.
• [41]Strang J, Best D, Man L, Noble A, Gossop M: Peer-initiated overdose resuscitation: fellow drug users could be mobilized to implement resuscitation. Int J Drug Policy 2000, 11(6):437.
• [42]Liu Y, Liang J, Zhao C, Zhou W: Looking for a solution for drug addiction in China: exploring the challenges and opportunities in the way of China's new Drug Control Law. Int J Drug Policy 2010, 21(3):149.