Etiology, treatment outcome and prognostic factors among patients with secondary peritonitis at Bugando Medical Centre, Mwanza, Tanzania

World Journal of Emergency Surgery

Japhet M. Gilyoma²  Stephen E. Mshana¹  Phillipo L. Chalya²  Jeremiah Seni¹  Amri Mabewa² 

[1] Department of Microbiology and Immunology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania;Department of Surgery, Bugando Medical Centre, Mwanza, Tanzania

关键词: Tanzania;    Secondary peritonitis;    Prognostic factors;    Treatment outcome;    Etiology;   

Others  :  1231290
DOI  :  10.1186/s13017-015-0042-5

 received in 2015-09-05, accepted in 2015-09-27,  发布年份 2015

【 摘 要 】

Introduction

Secondary peritonitis due to perforation of the gastrointestinal tract is one of the most common surgical emergencies all over the world and is associated with significantly morbidity and mortality. Previous studies conducted at Bugando Medical Centre (BMC) were retrospective and each was focused on single etiology; therefore there was an obvious need to evaluate the etiologies, treatment outcome and their prognostic factors altogether.

Methods

This was a descriptive cross-sectional study involving patients with secondary peritonitis admitted at BMC from May 2014 to April 2015. Sociodemographic and clinical characteristics among consented patients were collected using questionnaires. Peritoneal aspirate, biopsy and blood were collected perioperatively and processed using standard operating procedures. Analysis was done using STATA version 11 software.

Results

The study enrolled 97 patients with the female to male ratio of 1:1.8 and approximately 41.2 % (40/97) were in their third and fourth decades of life. Only 3 (3.09 %) patients arrived to the hospital within 24 hours of onset of illness, 26 (26.80 %) patients presented with shock and HIV seropositivity among all patients was 13.40 % (13/97). The common etiologies of secondary peritonitis were perforated appendicitis 23 (23.71 %), peptic ulcer disease 18 (18.56 %), ischemia 18 (18.56 %) and typhoidal perforation 15 (15.46 %). Of the 97 patients, 35 (36.08 %) had complications and 15 (15.46 %) died. Presence of premorbid illness and post-operative complication were found to be associated with death (p values = 0.004 and <0.001 respectively).

Conclusions

The most common etiologies of secondary peritonitis at BMC are perforated appendicitis, peptic ulcer disease, ischemia and typhoidal perforation. Premorbid illness and postoperative complications in this setting are associated with death and as the matter of fact proper screening on admission should be done to identify patients with premorbid illness and confer prompt management.

【 授权许可】

   
2015 Mabewa et al.

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