The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals

Retrovirology

Frank Kirchhoff¹  Rob A Gruters³  Albert D Osterhaus³  Marchina E van der Ende²  Daniela Krnavek¹  Xuehua Li¹  Mohammad Khalid¹  Christina M Stürzel¹  Julia Krämer¹  Alexandra Borch¹  Shariq M Usmani¹  Hangxing Yu¹ 

[1] Institute of Molecular Virology, Ulm University Medical Center, Ulm 89081, Germany;Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands;Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands

关键词: Viral immune sensing;    SAMHD1;    Vpx;    HIV-2;    AIDS;   

Others  :  1209152
DOI  :  10.1186/1742-4690-10-27

 received in 2012-08-21, accepted in 2013-02-22,  发布年份 2013

【 授权许可】

   
2013 Yu et al; licensee BioMed Central Ltd.

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