期刊论文详细信息
Source Code for Biology and Medicine | |
CADLIVE optimizer: web-based parameter estimation for dynamic models | |
Hiroyuki Kurata1  Shogo Takagi1  Shinpei Tonami1  Yuki Kato1  Kazuhiro Maeda1  Kentaro Inoue1  | |
[1] Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka, 820-8502, Japan | |
关键词: Dynamic model; Genetic algorithm; Optimization; Simulator; | |
Others : 806193 DOI : 10.1186/1751-0473-7-9 |
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received in 2012-04-25, accepted in 2012-08-15, 发布年份 2012 | |
【 摘 要 】
Computer simulation has been an important technique to capture the dynamics of biochemical networks. In most networks, however, few kinetic parameters have been measured in vivo because of experimental complexity. We develop a kinetic parameter estimation system, named the CADLIVE Optimizer, which comprises genetic algorithms-based solvers with a graphical user interface. This optimizer is integrated into the CADLIVE Dynamic Simulator to attain efficient simulation for dynamic models.
【 授权许可】
2012 Inoue et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
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20140708091132696.pdf | 944KB | download | |
Figure 2. | 40KB | Image | download |
Figure 1. | 103KB | Image | download |
【 图 表 】
Figure 1.
Figure 2.
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