Invasive ductal breast cancer metastatic to the sigmoid colon

World Journal of Surgical Oncology

Yi Jiang¹  Xiu-feng Zhang²  Ying-hai Ye³  Hong Zhou³  Xiao-cong Zhou³ 

[1] Department of Pathology, The Dingli Clinical Institute of Wenzhou Medical College (Wenzhou Central Hospital), Wenzhou, Zhejiang, P.R. China;Department of Colorectal Surgery, The Third People’s Hospital of Hangzhou, Hangzhou, Zhejiang, P.R. China;Department of Surgery, The Dingli Clinical Institute of Wenzhou Medical College (Wenzhou Central Hospital), Wenzhou, Zhejiang, P.R. China

关键词: Invasive ductal cancer;    Metastasis;    Sigmoid colon;    Breast cancer;   

Others  :  826824
DOI  :  10.1186/1477-7819-10-256

 received in 2012-05-02, accepted in 2012-10-24,  发布年份 2012

【 摘 要 】

The most common sites of breast cancer metastasis are the bone, lung, liver and brain. However, colonic metastases from breast cancer are very rare in the clinic. We describe an unusual case of sigmoid colonic metastasis from invasive ductal breast cancer. With this report, we should increase the clinical awareness that any patient with a colorectal lesion and a history of malignancy should be considered to have a metastasis until proven otherwise. Early diagnosis is very important, which enables prompt initiation of systemic treatment, such as chemotherapy, endocrine therapy or both, thus avoiding unnecessary radical surgical resection and improving the prognosis.

【 授权许可】

   
2012 Zhou et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

Figure 3.

Figure 4.

Figure 3.

Figure 6.

【 参考文献 】

• [1]Bamias A, Baltayiannis G, Kamina S, Fatouros M, Lymperopoulos E, Agnanti N, Tsianos E, Pavlidis N: Rectal metastases from lobular carcinoma of the breast: report of a case and literature review. Ann Oncol 2001, 12:715-718.
• [2]O’Connell FP, Wang HH, Odze RD: Utility of immunohistochemistry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract. Arch Pathol Lab Med 2005, 129:338-347.
• [3]Hye Jung C, Sae-Won H, Do-Youn O, Seock-Ah I, Yoon Kyung J, In Ae P, Wonshick H, Dong-Young N, Yung-Jue B, Tae-You K: Discordant human epidermal growth factor receptor 2 and hormone receptor status in primary and metastatic breast cancer and response to trastuzumab. Jpn J Clin Oncol 2011, 41:593-599.
• [4]Arslan C, Sari E, Aksoy S, Altundag K: Variation in hormone receptor and HER-2 status between primary and metastatic breast cancer: review of the literature. Expert Opin Ther Targets 2011, 15:21-30.
• [5]Taal BG, Den Hartog Jager FCA, Steinmetz R, Peterse H: The spectrum of gastrointestinal metastases of breast carcinoma: II. The colon and rectum. Gastrointest Endosc 1992, 38:136-141.
• [6]Schwarz RE, Klimstra DS, Turnbull AD: Metastatic breast cancer masquerading as gastrointestinal primary. Am J Gastroenterol 1998, 93:111-114.