Optimization of breast cancer excision by intraoperative ultrasound and marking needle - technique description and feasibility

World Journal of Surgical Oncology

Miroslav Granic³  Biljana Sredic²  Ivan Soldatovic⁴  Magdalena Stefanovic Radovic¹  Svetlana Opric⁵  Miodrag Stojiljkovic⁵  Natasa Colakovic²  Jelena Kostic²  Zlatko Skuric²  Darko D Zdravkovic³  Nebojsa S Ivanovic³ 

[1] Department of Radiology, UMC Bezanijska kosa, Autoput bb, Belgrade 11000, Serbia;Department of Surgical Oncology, UMC Bezanijska Kosa, Autoput bb, Belgrade 11000, Serbia;Medical Faculty of Belgrade University, Dr Subotica 8, Belgrade 11000, Serbia;Department of Statistics, Medical faculty of Belgrade University, Dr Subotica 8, Belgrade 11000, Serbia;Department of Pathology, UMC Bezanijska kosa, Autoput bb 11000, Belgrade, Serbia

关键词: Breast cancer;    Breast-conserving surgery;    Marking needle;    Intraoperative ultrasound;   

Others  :  1181829
DOI  :  10.1186/s12957-015-0568-8

 received in 2014-10-06, accepted in 2015-04-04,  发布年份 2015

【 摘 要 】

Background

We present a surgical technique and the preliminary results of breast cancer excision after insertion of a specially constructed marking needle into the tumor, controlled by intraoperative ultrasound.

Resection margins were projected in six directions by ultrasound measurements, determined in relation to the needle, and resection was done in accordance with those measurements. The main objective was to obtain resection margins similar (equal) to those projected by intraoperative ultrasound (10 mm).

Methods

Detailed description of the technique is given. Thirty-two female patients undergoing breast-conserving surgery, up to 30 mm in diameter, for palpable and non-palpable invasive breast cancer, were operated on using this technique. Its feasibility was tested by analyzing the success (rate) of needle placement in the tumor, the measurements executed, and the performance of the excision.

Results

All stages of the technique were successfully performed to completion on all 32 patients. The procedure of needle placement and ultrasound measurement of distances took 11 min on average (between 6 and 20 min). The average distance of the tumor margin from the resection margin was 12.9 mm (2 to 30 mm, 95% confidence interval [11.9, 14.06]). There was one patient with a positive resection margin (3%).

Conclusions

The technique of excising palpable and non-palpable breast cancer by intraoperative ultrasound and an especially constructed marking needle is feasible and comfortable to perform. Preliminary results imply that resection volume can be rationalized, with the same or better oncological safety.

【 授权许可】

   
2015 Ivanovic et al.; licensee BioMed Central.

【 图 表 】

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